验证 Skindex-17 生活质量评估工具在巴西人群中的适用性。

Validation of the Skindex-17 quality of life assessment instrument for a Brazilian population.

机构信息

Faculty of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.

出版信息

An Bras Dermatol. 2021 Jan-Feb;96(1):51-58. doi: 10.1016/j.abd.2020.03.021. Epub 2020 Nov 18.

DOI:10.1016/j.abd.2020.03.021

PMID:33281012

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7838104/

Abstract

BACKGROUND

Health-related quality of life assesses how diseases affect the daily life of people; there are several generic instruments for this assessment in dermatology. Skindex was created in 1996; it is a multidimensional instrument, aiming to encompass some psychological and social aspects not yet addressed by other questionnaires. Among its versions (Skindex-29, 16, and 17), Skindex-17 had not been validated in Brazil.

OBJECTIVES

To validate Skindex-17 for use in Brazilians with dermatological diseases.

METHODS

This was a methodological, cross-sectional, and prospective study of 217 patients attended at the Dermatology Service Outpatient Clinic, Faculdade de Medicina de Botucatu - Universidade Estadual Paulista (Botucatu, SP, Brazil), from December 2017 to September 2019. The following were evaluated: content validity, filling time, internal consistency, dimensional structure, concurrent validity (DLQI), temporal stability, and responsiveness.

RESULTS

The sample consisted of 71% women, mean age (SD) of 45 (16) years; phototypes II-IV accounted for 95% of the cases. Cronbach's alpha coefficients were 0.82 and 0.93 for the symptoms and psychosocial conditions, respectively. A high correlation was observed with the DLQI score: symptoms (rho = 0.69) and psychosocial conditions (rho = 0.75). The instrument's two-dimensional structure was confirmed through confirmatory factor analysis. Temporal stability (ICC > 0.9) and score responsiveness (p ≤ 0.02) were verified. The instrument was shown to be feasible in clinical practice due to the content validation performed by professionals and patients, as well as the low time spent completing it (< 5 min).

STUDY LIMITATIONS

Single-center study, with patients exclusively from the public healthcare system.

CONCLUSIONS

Skindex-17 was shown to be a valid and consistent instrument for assessing quality of life among patients with dermatological diseases, in Brazil. Its two-dimensional structure was confirmed.

摘要

背景

健康相关生活质量评估疾病如何影响人们的日常生活；皮肤科有几种通用的评估工具。Skindex 于 1996 年创建；它是一个多维工具，旨在涵盖其他问卷尚未涉及的一些心理和社会方面。在其版本（Skindex-29、16 和 17）中，Skindex-17 尚未在巴西得到验证。

目的

验证 Skindex-17 用于评估巴西皮肤科疾病患者的生活质量。

方法

这是一项方法学、横断面和前瞻性研究，共纳入 217 名于 2017 年 12 月至 2019 年 9 月在巴西博图卡图市圣保罗州立大学医学院皮肤科门诊就诊的患者。评估内容包括内容效度、填写时间、内部一致性、维度结构、并行效度（DLQI）、时间稳定性和反应性。

结果

样本包括 71%的女性，平均（SD）年龄为 45（16）岁；95%的病例为皮肤类型 II-IV。症状和心理社会状况的克朗巴赫 α 系数分别为 0.82 和 0.93。与 DLQI 评分相关性较高：症状（rho=0.69）和心理社会状况（rho=0.75）。通过验证性因子分析证实了该工具的二维结构。时间稳定性（ICC>0.9）和评分反应性（p≤0.02）得到验证。该工具在临床实践中是可行的，因为专业人员和患者对其进行了内容验证，并且完成它所需的时间很短（<5 分钟）。