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80岁及以上高龄老人中的衰弱综合征:患病率及相关因素

Frailty Syndrome among oldest old Individuals, aged ≥80 years: Prevalence & Correlates.

作者信息

Sharma Pawan Kumar, Reddy Bana Manishaa, Ganguly Enakshi

机构信息

Department of Community Medicine, Mediciti Institute of Medical Sciences, Ghanpur, Hyderabad, India.

Department of Epidemiology, University of Pittsburgh, and SHARE INDIA, Fogarty International, NIH.

出版信息

J Frailty Sarcopenia Falls. 2020 Dec 1;5(4):92-101. doi: 10.22540/JFSF-05-092. eCollection 2020 Dec.

Abstract

OBJECTIVES

Objectives were to study prevalence of frailty among Indian oldest old population, and to detect its correlates.

METHODS

A cross sectional community based study was done including 200 healthy participants aged ≥80 years, randomly sampled from Hyderabad city in India. They completed an administered questionnaire and physical function tests including SPPB, grip strength. Cognitive function was assessed using MMSE and depression using GDS. Blood pressure, haemoglobin, and fasting blood sugar were measured for all participants. Frailty was defined using Fried phenotype criteria. Logistic regression was done to identify independently associated correlates.

RESULTS

The prevalence of frailty syndrome was 83.4% in our study population. Frailty among men was 80.3% and among women was 84.7%, and it increased with increasing age. The independent correlates which increased the odds of frailty were poor physical performance (SPPB) (OR: 4.21; 95% CI: 1.12-15.83), depression (OR: 3.35; 95% CI: 1.29-8.73), chronic joint pains (OR: 4.90; 95% CI: 1.97-12.18) and COPD (OR: 3.01; 95% CI: 1.03- 8.78), while hypertension showed inverse association (OR: 0.33;95% CI: 0.11-0.94).

CONCLUSION

The prevalence of frailty among the oldest old is very high. Geriatric medicine protocols must include routine screening for frailty, while also including early detection of poor physical performance, depression, COPD and osteoarthritis.

摘要

目的

研究印度高龄人群中衰弱的患病率,并找出其相关因素。

方法

开展了一项基于社区的横断面研究,纳入了200名年龄≥80岁的健康参与者,这些参与者是从印度海得拉巴市随机抽取的。他们完成了一份调查问卷以及包括简易体能状况量表(SPPB)、握力在内的身体功能测试。使用简易精神状态检查表(MMSE)评估认知功能,使用老年抑郁量表(GDS)评估抑郁状况。测量了所有参与者的血压、血红蛋白和空腹血糖。采用弗里德表型标准定义衰弱。进行逻辑回归分析以确定独立相关的因素。

结果

在我们的研究人群中,衰弱综合征的患病率为83.4%。男性衰弱患病率为80.3%,女性为84.7%,且随年龄增长而增加。增加衰弱几率的独立相关因素包括身体表现差(SPPB)(比值比:4.21;95%置信区间:1.12 - 15.83)、抑郁(比值比:3.35;95%置信区间:1.29 - 8.73)、慢性关节疼痛(比值比:4.90;95%置信区间:1.97 - 12.18)和慢性阻塞性肺疾病(COPD)(比值比:3.01;95%置信区间:1.03 - 8.78),而高血压呈现负相关(比值比:0.33;95%置信区间:0.11 - 0.94)。

结论

高龄人群中衰弱的患病率非常高。老年医学方案必须包括对衰弱的常规筛查,同时还应包括对身体表现差、抑郁、COPD和骨关节炎的早期检测。

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