Hospital Israelita Albert Einstein, São Paulo, Brazil.
Department of Health Sciences, Lehman College, CUNY, Bronx, NY, USA.
Scand J Med Sci Sports. 2021 Mar;31(3):498-509. doi: 10.1111/sms.13902. Epub 2020 Dec 22.
Low-intensity resistance exercise with blood flow restriction exercise is an emerging type of exercise recognition worldwide. This systematic review evaluated the effects of low-intensity resistance exercise performed with concurrent blood flow restriction (LIRE-BFR) on acute and chronic measures of arterial stiffness in humans. A systematic search in six healthcare science databases and reference lists was conducted. Data selected for primary analysis consisted of post-intervention changes in arterial stiffness markers. This systematic review included randomized and non-randomized controlled trials of LIRE-BFR in humans. 156 articles were initially identified, 15 of which met inclusion criteria. Ten studies were excluded because they did not match predefined arterial stiffness markers. Thus, five articles were included in this review: two acute studies (N = 39 individuals, age = 20-30 years old, 30.8% women and 69.2% men) and three longitudinal studies (N = 51 individuals, age = 24-86-years old, 41.2% women and 58.8% men). Acute LIRE-BFR demonstrated both positive and negative effects on arterial stiffness in healthy young people. In contrast, longitudinal studies reported neutral effects in healthy young and older people. In conclusion, LIRE-BFR applied to the upper and lower limbs may acutely induce increases in central blood pressure and pulse wave velocity in healthy young people, whereas LIRE-BFR for the lower limbs may elicit positive effects related to indirect markers of arterial stiffness. Moreover, longitudinal LIRE-BFR studies showed no changes in arterial stiffness in young and older people. Hence, LIRE-BFR should be prescribed with a degree of caution to avoid non-intended responses in arterial stiffness markers in humans.
低强度抗阻运动结合血流限制训练是一种在全球范围内新兴的运动方式。本系统评价评估了低强度抗阻运动结合血流限制（LIRE-BFR）对人体急性和慢性动脉僵硬度指标的影响。在六个健康科学数据库和参考文献列表中进行了系统检索。选择进行主要分析的数据包括动脉僵硬标志物的干预后变化。本系统评价纳入了 LIRE-BFR 在人体中的随机和非随机对照试验。最初确定了 156 篇文章，其中 15 篇符合纳入标准。由于不符合预定义的动脉僵硬标志物，10 项研究被排除在外。因此，本综述纳入了 5 篇文章：2 项急性研究（N=39 人，年龄 20-30 岁，女性占 30.8%，男性占 69.2%）和 3 项纵向研究（N=51 人，年龄 24-86 岁，女性占 41.2%，男性占 58.8%）。急性 LIRE-BFR 在健康年轻人中对动脉僵硬度产生了积极和消极的影响。相比之下，纵向研究报告了健康年轻和老年人的中性影响。总之，LIRE-BFR 施加于上下肢可能会在健康年轻人中急性引起中心血压和脉搏波速度的增加，而下肢的 LIRE-BFR 可能会引起与动脉僵硬度间接标志物相关的积极影响。此外，纵向 LIRE-BFR 研究显示年轻人和老年人的动脉僵硬度没有变化。因此，LIRE-BFR 的应用应谨慎，以避免在人体动脉僵硬度标志物中产生非预期的反应。
