Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University , Ft. Lauderdale, FL, USA.
Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University , Ft. Lauderdale, FL, USA.
Electromagn Biol Med. 2021 Jan 2;40(1):1-10. doi: 10.1080/15368378.2020.1856682. Epub 2020 Dec 5.
This pilot study's goal was to investigate the impacts of static magnetic fields (SMF) on finger skin blood perfusion (SBP) when exposing the ulnar artery and ulnar and medial nerves to a rare earth concentric magnet for 30 minutes. Control SBP was measured in 4 fingers of adults (n = 12, age 26.0 ± 1.4 years) for 15 minutes using laser-Doppler. Then, active-magnets were placed over one arm's ulnar and median nerves at the wrist and sham-magnets placed at corresponding sites on the other arm. Devices were randomly assigned and placed by an investigator "blinded" to device type. The maximum SMF perpendicular to skin was 0.28 T measured 2 mm from magnet surface. The tangential field at this distance was 0.20 T. SBP was analyzed and tested for differential effects attributable to magnets compared to shams in each of the 5-minute intervals over the full 45-minute experiment. Results showed no statistically significant difference between SBP measured on the magnet-treated side compared to the sham side. Magnet and sham side SBP values (mean ± SEM, arbitrary units) prior to device placement were 0.568 ± 0.128 vs. 0.644 ± 0.115, = .859 and during device placement were 0.627 ± 0.135 vs. 0.645 ± 0.117, = .857. In conclusion, these findings have failed to uncover any significant effects of the static magnetic field on skin blood perfusion in the young healthy adult population evaluated. Its potential for altering SBP in more mature persons or those with underlying conditions affecting blood flow has not been evaluated but represents the next target of research inquiry. ClinicalTrials.gov registration number is NCT04539704.
这项初步研究的目的是在将稀土同心磁体置于腕部的尺动脉和尺神经及正中神经上 30 分钟后，研究静磁场（SMF）对指皮血流灌注（SBP）的影响。使用激光多普勒法在成年人的 4 个手指（n=12，年龄 26.0±1.4 岁）上测量 15 分钟的对照 SBP。然后，在一只手臂的尺神经和正中神经以及另一只手臂的相应部位上放置活动磁铁和假磁铁。通过一名对设备类型“盲法”的研究人员随机分配和放置设备。在整个 45 分钟的实验中，在每个 5 分钟的间隔内，分析并测试了 SBP，以测试与磁铁相比，磁铁和假磁铁在 5 分钟间隔内的差异。结果显示，在治疗侧和假侧测量的 SBP 之间没有统计学上的显著差异。在放置设备之前，磁铁处理侧和假侧的 SBP 值（均值±SEM，任意单位）分别为 0.568±0.128 对 0.644±0.115， = 0.859 和在放置设备期间分别为 0.627±0.135 对 0.645±0.117， = 0.857。总之，这些发现未能揭示静磁场对年轻健康成年人皮肤血流灌注的任何显著影响。尚未评估其对更成熟的人或那些有影响血流的潜在疾病的人改变 SBP 的潜力，但这是下一步研究的目标。临床试验注册号为 NCT04539704。
