Huang Shouqiang, Fan Qian, Xiong Jun, Liao Kai, Hua Fanghui, Xiang Jie, Li Changsheng, Jin Hangyu
Jiangxi University of Traditional Chinese Medicine, Nanchang.
Changshu Hospital of Traditional Chinese Medicine, Changshu.
Medicine (Baltimore). 2020 Dec 4;99(49):e22372. doi: 10.1097/MD.0000000000022372.
De Quervain's tenosynovitis is an overuse disease that involves a thickening of the abductor pollicis longus and extensor pollicis brevis tendons. Evidence shows that acupuncture and moxibustion (AM) could remarkably relieve the pain of De Quervain's tenosynovitis patients. The aim of this protocol is to determine the efficacy and safety of AM for treating De Quervain's tenosynovitis.
Several online databases including PubMed, Cochrane Library, Embase, Chinese Biomedical Literatures Database, China National Knowledge Infrastructure, WangFang Database, Chinese Scientific Journal Database will be searched from their establishment to July 1, 2020. We will include all randomized controlled trials using AM as the method for treating De Quervain's tenosynovitis, regardless of blinding or publication types. The selection of studies, data extraction and the assessment of the studies quality will be conducted by 2 reviewers separately. When there is sufficient available data for meta-analysis, we will use the RevMan V.5.3 statistical software for data synthesis. The total effective rate, range of motion of wrist ulnar deviation will be the primary outcomes, and the secondary outcomes contain Visual Analog Scale, Coney Wrist Score and side effects. We will express the result by using Risk ratio for dichotomous data and mean differences with a 95% confidence interval for continuous data.
The results of this study be presented in corresponding journal or conferences.
This study is designed to provide sufficient evidence to assess the exact effectiveness of AM on De Quervain's tenosynovitis.
CRD42020158764.
桡骨茎突狭窄性腱鞘炎是一种过度使用导致的疾病，涉及拇长展肌和拇短伸肌腱增厚。有证据表明，针灸对桡骨茎突狭窄性腱鞘炎患者的疼痛有显著缓解作用。本方案的目的是确定针灸治疗桡骨茎突狭窄性腱鞘炎的疗效和安全性。
检索包括PubMed、Cochrane图书馆、Embase、中国生物医学文献数据库、中国知网、万方数据库、维普数据库在内的多个在线数据库，检索时间从建库至2020年7月1日。我们将纳入所有使用针灸作为治疗桡骨茎突狭窄性腱鞘炎方法的随机对照试验，无论是否设盲或出版类型。研究的筛选、数据提取和研究质量评估将由2名 reviewers 分别进行。当有足够的可用数据进行荟萃分析时，我们将使用RevMan V.5.3统计软件进行数据合成。总有效率、腕尺偏活动度将作为主要结局指标，次要结局指标包括视觉模拟评分、Coney腕关节评分和副作用。对于二分数据，我们将使用风险比来表示结果，对于连续数据，我们将使用95%置信区间的均值差来表示结果。
本研究结果将在相应的期刊或会议上发表。
本研究旨在提供充分的证据，以评估针灸治疗桡骨茎突狭窄性腱鞘炎的确切有效性。
PROSPERO注册号：CRD42020158764。
