Zhou Tian'an, Jiang Hui, Wang Yang, Xie Chen, Xia Jianhua, Shen Ye
Department of Ophthalmology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Medicine (Baltimore). 2020 Dec 4;99(49):e23434. doi: 10.1097/MD.0000000000023434.
The aim of this study was to compare the anterior chamber angle changes after implantation of phakic intraocular lens with and without a central hole for moderate to high myopic eyes in Chinese people.This study enrolled 106 eyes of 54 people with intraocular lens V4 implantation and 105 eyes of 53 people with intraocular lens V4c implantation. Postoperative vault, intraocular pressure, and anterior chamber angle changes were assessed using noncontract tonometer and ultrasound biomicroscope, respectively, at 1, 3, 6, and 12months after the surgery.There were no significant differences (all P > .05) between the 2 groups in the depth of the central vault, intraocular pressure, or the width of anterior chamber angle at any time point post-surgery. The anterior chamber angle width in degree had a baseline of 54.40 ± 10.51 in V4c group, and decreased to 27.80 ± 5.62, 26.95 ± 5.56, 27.32 ± 5.66, 27.04 ± 5.47 at 1, 3, 6, and 12 months post-surgery, respectively. Mean preoperative value of 50.62 ± 11.77 decreased to 27.28 ± 6.53, 26.82 ± 6.03, 26.61 ± 5.80, 26.83 ± 5.76 at 1, 3, 6, 12 months, respectively, in V4 group. It had sufficient evidence (P < .001) that anterior chamber angle will narrow done after surgery, but there were no statistically significant differences within groups at any time point after surgery.The anterior chamber angle changes of the V4c group was essentially equivalent to that of conventional V4 group, although implantation of both models will lead to the decrease in anterior chamber angle width.
本研究旨在比较植入有或没有中心孔的有晶状体眼人工晶状体后,中国人中、高度近视眼中前房角的变化。本研究纳入了54例接受V4型人工晶状体植入的患者的106只眼和53例接受V4c型人工晶状体植入的患者的105只眼。分别在术后1、3、6和12个月使用非接触眼压计和超声生物显微镜评估术后拱高、眼压和前房角变化。两组在术后任何时间点的中央拱高深度、眼压或前房角宽度均无显著差异(所有P>0.05)。V4c组前房角宽度(度数)基线为54.40±10.51,术后1、3、6和12个月分别降至27.80±5.62、26.95±5.56、27.32±5.66、27.04±5.47。V4组术前平均数值50.62±11.77在术后1、3、6、12个月分别降至27.28±6.53、26.82±6.03、26.61±5.80、26.83±5.76。有充分证据(P<0.001)表明术后前房角会变窄,但术后各时间点组内无统计学显著差异。V4c组的前房角变化与传统V4组基本相当,尽管两种型号的植入都会导致前房角宽度减小。