Deng Gen, Ye Wenguo, Wan Qun, Wang Jinlong
College of Acupuncture and Massage, Jiangxi University of Traditional Chinese Medicine.
Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, China.
Medicine (Baltimore). 2020 Dec 4;99(49):e23481. doi: 10.1097/MD.0000000000023481.
Urticaria is a common skin disease in clinic. The main clinical symptoms are sudden attack, various forms, different sizes of wind, and erythema, accompanied by varying degrees of itching. At present, antihistamines, non-specific antiallergic agents, or glucocorticoids are the main treatment, with some side effects and adverse reactions. Moxibustion therapy has shown strong advantages in the treatment of urticaria, and the curative effect is accurate. Therefore, this paper will carry out a systematic evaluation and meta-analysis of the efficacy and safety of moxibustion in the treatment of urticaria.
Eight electronic databases will be searched, including PubMed, Excerpta Medica Database, Web of Science, Cochrane Library, the China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang Database (WF), and Chinese Biomedical Literature Database (CBM). We will search above electronic databases from the beginning to October 2020, without any language restriction, but involving only the human subjects. Clinical efficacy, including total effective rate or cure rate, and recurrence rate will be accepted as the primary outcomes. The itch level, number of clusters, size of clusters, and laboratory test results will be used as secondary outcomes. The Cochrane Handbook of Systematic Review (5.3.0) RCT risk assessment tool will be used to evaluate the risk of bias by 2 independent researchers.
After the completion of this study, the results will be reported, so it is not possible to give accurate results at present.
The results of this study will provide reliable evidence for the efficacy and safety of moxibustion in the treatment of urticaria.
INPLASY2020100040.
荨麻疹是临床上常见的皮肤病。主要临床症状为突然发作，形态多样，大小不一的风团及红斑，并伴有不同程度的瘙痒。目前，抗组胺药、非特异性抗过敏药或糖皮质激素是主要治疗手段，但存在一些副作用和不良反应。艾灸疗法在荨麻疹治疗中显示出强大优势，疗效确切。因此，本文将对艾灸治疗荨麻疹的疗效和安全性进行系统评价和荟萃分析。
检索八个电子数据库，包括PubMed、医学文摘数据库、科学引文索引数据库、考克兰图书馆、中国知网、维普中文科技期刊数据库、万方数据库和中国生物医学文献数据库。检索上述电子数据库至2020年10月，无语言限制，但仅涉及人类受试者。临床疗效，包括总有效率或治愈率以及复发率将作为主要结局。瘙痒程度、风团数量、风团大小和实验室检查结果将作为次要结局。将使用考克兰系统评价手册（5.3.0）随机对照试验风险评估工具由两名独立研究人员评估偏倚风险。
本研究完成后将报告结果，因此目前无法给出准确结果。
本研究结果将为艾灸治疗荨麻疹的疗效和安全性提供可靠证据。
INPLASY注册号：INPLASY2020100040。
