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Medical Therapy for Heart Failure Caused by Ischemic Heart Disease.缺血性心脏病引起的心力衰竭的医学治疗。
Circ Res. 2019 May 24;124(11):1520-1535. doi: 10.1161/CIRCRESAHA.118.313568.
2
Heart Failure With Preserved Ejection Fraction In Perspective.射血分数保留的心力衰竭观点述评。
Circ Res. 2019 May 24;124(11):1598-1617. doi: 10.1161/CIRCRESAHA.119.313572.
3
Improving care for patients with acute heart failure: before, during and after hospitalization.改善急性心力衰竭患者的护理:住院前、住院期间及出院后。
ESC Heart Fail. 2014 Dec;1(2):110-145. doi: 10.1002/ehf2.12021. Epub 2015 Jan 21.
4
Biomarker Profiles in Heart Failure Patients With Preserved and Reduced Ejection Fraction.心力衰竭患者保留和降低射血分数的生物标志物特征。
J Am Heart Assoc. 2017 Mar 30;6(4):e003989. doi: 10.1161/JAHA.116.003989.
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Prevalence of atrial fibrillation in the Malaysian communities.马来西亚社区中心房颤动的患病率。
Heart Asia. 2016 Nov 18;8(2):62-66. doi: 10.1136/heartasia-2016-010775. eCollection 2016.
6
Comparison of Characteristics and Outcomes of Heart Failure Patients With Preserved Versus Reduced Ejection Fraction in a Multiethnic Southeast Asian Cohort.多民族东南亚队列中射血分数保留与降低的心力衰竭患者的特征及结局比较
Am J Cardiol. 2016 Oct 15;118(8):1233-1238. doi: 10.1016/j.amjcard.2016.07.039. Epub 2016 Jul 29.
7
N-terminal pro b-type natriuretic peptide (NT-pro-BNP) -based score can predict in-hospital mortality in patients with heart failure.基于 N 端脑利钠肽前体(NT-pro-BNP)的评分可以预测心力衰竭患者的住院死亡率。
Sci Rep. 2016 Jul 14;6:29590. doi: 10.1038/srep29590.
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Heart Failure Clinical Trials in East and Southeast Asia: Understanding the Importance and Defining the Next Steps.东亚和东南亚地区的心力衰竭临床试验:理解其重要性并明确下一步行动
JACC Heart Fail. 2016 Jun;4(6):419-27. doi: 10.1016/j.jchf.2016.01.013.
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2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.2016欧洲心脏病学会急性和慢性心力衰竭诊断与治疗指南:欧洲心脏病学会(ESC)急性和慢性心力衰竭诊断与治疗工作组编写,欧洲心脏病学会心力衰竭协会(HFA)提供特别贡献。
Eur Heart J. 2016 Jul 14;37(27):2129-2200. doi: 10.1093/eurheartj/ehw128. Epub 2016 May 20.
10
Heart failure care in low- and middle-income countries: a systematic review and meta-analysis.低收入和中等收入国家的心力衰竭护理:系统评价与荟萃分析
PLoS Med. 2014 Aug 12;11(8):e1001699. doi: 10.1371/journal.pmed.1001699. eCollection 2014 Aug.

沙捞越综合医院(SGH-HF)非心血管病三级转诊中心的急性失代偿性心力衰竭。

Acute decompensated heart failure in a non cardiology tertiary referral centre, Sarawak General Hospital (SGH-HF).

机构信息

Medical Department, Sarawak General Hospital (SGH), Kuching, Malaysia.

Faculty of Medicine and Health Sciences, University Malaysia Sarawak (UNIMAS), Jalan Datuk Mohammad Musa, 94300, Kota Samarahan, Sarawak, Malaysia.

出版信息

BMC Cardiovasc Disord. 2020 Dec 7;20(1):511. doi: 10.1186/s12872-020-01793-7.

DOI:10.1186/s12872-020-01793-7
PMID:33287705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7720602/
Abstract

BACKGROUND

Data on clinical characteristics of acute decompensated heart failure (ADHF) in Malaysia especially in East Malaysia is lacking.

METHODS

This is a prospective observational study in Sarawak General Hospital, Medical Department, from October 2017 to September 2018. Patients with primary admission diagnosis of ADHF were recruited and followed up for 90 days. Data on patient's characteristics, precipitating factors, medications and short-term clinical outcomes were recorded.

RESULTS

Majority of the patients were classified in lower socioeconomic group and the mean age was 59 years old. Hypertension, diabetes mellitus and dyslipidaemia were the common underlying comorbidities. Heart failure with ischemic aetiology was the commonest ADHF admission precipitating factor. 48.6% of patients were having preserved ejection fraction HF and the median NT-ProBNP level was 4230 pg/mL. Prescription rate of the evidence-based heart failure medication was low. The in-patient mortality and the average length of hospital stay were 7.5% and 5 days respectively. 43% of patients required either ICU care or advanced cardiopulmonary support. The 30-day, 90-day mortality and readmission rate were 13.1%, 11.2%, 16.8% and 14% respectively.

CONCLUSION

Comparing with the HF data from West and Asia Pacific, the short-term mortality and readmission rate were high among the ADHF patients in our study cohort. Maladaptation to evidence-based HF prescription and the higher prevalence of cardiovascular risk factors in younger patients were among the possible issues to be addressed to improve the HF outcome in regions with similar socioeconomic background.

摘要

背景

马来西亚,尤其是东马来西亚,缺乏关于急性失代偿性心力衰竭(ADHF)临床特征的数据。

方法

这是 2017 年 10 月至 2018 年 9 月在砂拉越总医院内科进行的一项前瞻性观察研究。招募了以 ADHF 为主要入院诊断的患者,并对其进行了 90 天的随访。记录了患者的特征、诱发因素、药物治疗和短期临床结局的数据。

结果

大多数患者来自较低社会经济群体,平均年龄为 59 岁。高血压、糖尿病和血脂异常是常见的合并症。心力衰竭的缺血性病因是最常见的 ADHF 入院诱发因素。48.6%的患者射血分数保持正常,中位 NT-ProBNP 水平为 4230pg/ml。基于证据的心力衰竭药物的处方率较低。住院死亡率和平均住院天数分别为 7.5%和 5 天。43%的患者需要重症监护或高级心肺支持。30 天、90 天死亡率和再入院率分别为 13.1%、11.2%、16.8%和 14%。

结论

与西方和亚太地区的心力衰竭数据相比,我们研究队列中的 ADHF 患者短期死亡率和再入院率较高。在社会经济背景相似的地区,可能需要解决适应基于证据的心力衰竭处方和年轻患者心血管风险因素高发的问题,以改善心力衰竭结局。