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急性心力衰竭是一个恶性过程:但我们可以诱导缓解。

Acute Heart Failure Is a Malignant Process: But We Can Induce Remission.

机构信息

Heart Initiative Durham NC.

Momentum Research, Inc Durham NC.

出版信息

J Am Heart Assoc. 2023 Nov 7;12(21):e031745. doi: 10.1161/JAHA.123.031745. Epub 2023 Oct 27.

DOI:10.1161/JAHA.123.031745
PMID:37889197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10727371/
Abstract

Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcomes, it represents one of the largest drivers of health care costs globally. Studies in the past 2 years have demonstrated that we can induce remissions in this malignant process if therapy is instituted rapidly, at the first acute heart failure episode, using full doses of all available effective medications. Multiple studies have demonstrated that this goal can be achieved safely and effectively. Now the urgent call is for all stakeholders, patients, physicians, payers, politicians, and the public at large to come together to address the gaps in implementation and enable health care providers to induce durable remissions in patients with acute heart failure.

摘要

急性心力衰竭是一种常见且日益流行的病症,每年影响超过 1000 万人。对于那些存活至出院的患者,全球各地的早期再入院率和死亡率均>30%,使其成为一种恶性病症。除了这些不良后果外,它还是导致全球医疗保健成本的最大驱动因素之一。过去 2 年来的研究表明,如果在首次急性心力衰竭发作时迅速采用所有现有有效药物的全剂量进行治疗,我们可以诱导该恶性过程的缓解。多项研究表明,这一目标可以安全有效地实现。现在,当务之急是让所有利益相关者——患者、医生、支付方、政客和广大公众——共同努力,解决实施方面的差距,使医疗保健提供者能够诱导急性心力衰竭患者获得持久缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc1/10727371/391e2981ecca/JAH3-12-e031745-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc1/10727371/391e2981ecca/JAH3-12-e031745-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebc1/10727371/391e2981ecca/JAH3-12-e031745-g001.jpg

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