采用标准化方案治疗瘢痕疙瘩的长期疗效和无复发生存期。
Long-term outcomes and recurrence-free interval after the treatment of keloids with a standardized protocol.
机构信息
Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan.
Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan; Department of Oral and Maxillofacial Surgery, Graduate School of Dental Medicine, Hokkaido University, Japan.
出版信息
J Tissue Viability. 2021 Feb;30(1):128-132. doi: 10.1016/j.jtv.2020.11.003. Epub 2020 Nov 30.
BACKGROUND
Recurrence rates of keloids have generally been reported at one time point. However, the longer the duration after treatment, the greater the likelihood that such lesions will recur. In this study, we analysed the time to recurrence during long-term follow-up.
MATERIAL AND METHODS
We retrospectively reviewed recurrence-free interval in 52 patients with keloid (age 8-79 years) who had been treated between June 2006 and January 2011 using a standardised protocol developed by our group.
RESULTS
Mean duration of follow-up was 37.5 (range, 7-120) months in patients with keloid. Kaplan-Meier survival curves revealed a statistically significant difference in recurrence-free interval between ear keloids and keloids excluding ear keloids. Recurrence rate for keloids was high in the first 2 years after treatment.
CONCLUSIONS
Kaplan-Meier analysis was useful for understanding the tendency of recurrence of keloids after treatment using a standardised protocol.
背景
瘢痕疙瘩的复发率通常在一个时间点报告。然而，治疗后时间越长，这些病变复发的可能性就越大。在这项研究中，我们分析了长期随访期间的复发时间。
材料和方法
我们回顾性分析了 2006 年 6 月至 2011 年 1 月期间，使用我们小组制定的标准化方案治疗的 52 例瘢痕疙瘩（年龄 8-79 岁）患者的无复发间隔。
结果
瘢痕疙瘩患者的平均随访时间为 37.5（范围 7-120）个月。Kaplan-Meier 生存曲线显示，耳瘢痕疙瘩和非耳瘢痕疙瘩之间的无复发间隔有统计学显著差异。治疗后前 2 年瘢痕疙瘩的复发率较高。
结论
Kaplan-Meier 分析对于理解使用标准化方案治疗后瘢痕疙瘩复发的趋势很有用。
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