Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Jongno-Gu, Seoul, 110-746, Korea.
Aesthetic Plast Surg. 2012 Feb;36(1):169-73. doi: 10.1007/s00266-011-9781-1. Epub 2011 Jul 7.
The physiopathogenesis of keloid scars is not well understood. This report aims to present the authors' experiences with facial keloids, to evaluate their treatment outcomes via a prospective study, and to identify risk factors involved in facial keloid recurrence.
Patients with facial keloids were treated with surgical excision followed by intra- and postoperative intralesional steroid injections at Kangbuk Samsung Hospital between July 2005 and June 2010. Of 15 keloids, 8 (53.3%) had previously been treated unsuccessfully at other hospitals. The follow-up period was 18 months, and therapeutic outcomes were evaluated based on recurrence or nonrecurrence.
The study evaluated 17 facial keloids in 15 patients. The overall recurrence-free rate was 76.5% after a follow-up period of 18 months. The authors hypothesized that the recurrence of keloids on the face is associated with both previous treatment and anatomic location.
The authors' protocol resulted in successful outcomes for the treatment of facial keloids. Patients with a history of previous treatment and keloids in the perioral region should be monitored closely for signs of recurrence and managed cautiously during treatment.
瘢痕疙瘩的病理生理学机制尚未完全明确。本研究旨在报告作者在面部瘢痕疙瘩治疗方面的经验，通过前瞻性研究评估其治疗效果，并确定与面部瘢痕疙瘩复发相关的危险因素。
2005 年 7 月至 2010 年 6 月，在康伯斯三星医院对 15 例面部瘢痕疙瘩患者采用手术切除联合术后局部皮质类固醇注射治疗。其中 8 例（53.3%）先前在其他医院治疗失败。随访时间为 18 个月，根据复发或非复发情况评估治疗效果。
研究共评估了 15 例患者的 17 处面部瘢痕疙瘩。18 个月的随访期后，无复发率为 76.5%。作者假设面部瘢痕疙瘩的复发与既往治疗和解剖位置有关。
作者的方案对面部瘢痕疙瘩的治疗取得了成功的效果。对于有既往治疗史和口周区域瘢痕疙瘩的患者，应密切监测复发迹象，并在治疗过程中谨慎处理。
