Huang Chuan, Yang Xue
Department of Thoracic Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Department of Thoracic Medical Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China.
Thorac Cancer. 2020 Dec 1;12(3):391-6. doi: 10.1111/1759-7714.13769.
Malignant pleural mesothelioma (MPM) is a rare neoplasm of the serosal membranes. MPM usually manifests as local invasion, rarely with distant haematogenous metastases in different organs. Few cases of tongue metastasis have been documented. Here, we report the case of a 68-year-old man diagnosed with malignant pleural epithelioid mesothelioma together with a simultaneous tongue lesion, which was found to be metastatic malignant mesothelioma. Tongue metastasis from MPM is rare and the oral symptoms it causes could be an early sign of clinical manifestation. For patients with oral symptoms and a newly discovered tongue lesion, clinicians should be aware of the possibility of tongue metastasis and search for a primary malignancy.
恶性胸膜间皮瘤(MPM)是一种罕见的浆膜肿瘤。MPM通常表现为局部侵袭,很少在不同器官发生远处血行转移。舌转移的病例记载较少。在此,我们报告一例68岁男性患者,诊断为恶性胸膜上皮样间皮瘤,同时伴有舌部病变,经发现为转移性恶性间皮瘤。MPM发生舌转移很罕见,其引起的口腔症状可能是临床表现的早期迹象。对于有口腔症状且新发现舌部病变的患者,临床医生应意识到舌转移的可能性,并寻找原发性恶性肿瘤。