Defence Research and Development Establishment, Jhansi Road, Gwalior 474002, India.
Anal Chem. 2021 Jan 19;93(2):1193-1199. doi: 10.1021/acs.analchem.0c04464. Epub 2020 Dec 8.
We have explored a novel turn-on fluorescence detection of sulfur mustard (SM) at "room temperature". The innovative protocol that uses the combination of luminol and an ionic liquid in water exhibits fluorescence detection of SM within seconds. In this simple, fast, and low-cost chemosensing method, luminol acts as the receptor as well as a signaling element, and the ionic liquid (1-ethyl-3-methylimidazolium dicyanamide) provides the requisite and polarizing medium to realize the detection at "room temperature". Interestingly, with a higher concentration of a probe (0.56 mM), SM sensing can be visualized with the naked eye, leading to the formation of a fluorescent green color within a minute, thus expanding the application of the developed sensing technique for chromo-fluorogenic detection of SM. Excellent selectivity, sensitivity (LOD: 6 ppm), and chemosensing at ambient temperature make this methodology completely field-deployable.
我们探索了一种新颖的室温下硫芥（SM）的荧光检测方法。该创新方案结合了水中的鲁米诺和离子液体，可在几秒钟内对 SM 进行荧光检测。在这种简单、快速且低成本的化学传感方法中，鲁米诺既是受体又是信号元件，而离子液体（1-乙基-3-甲基咪唑二氰胺）则提供必需的极性介质，以实现室温下的检测。有趣的是，探针浓度较高（0.56mM）时，SM 传感可以用肉眼观察到，在一分钟内形成荧光绿色，从而扩展了所开发的传感技术在 SM 的比色荧光检测中的应用。出色的选择性、灵敏度（LOD：6ppm）和室温下的化学传感使该方法完全可现场部署。
