Mengoni M, Tüting T, Gaffal E
Universitätshautklinik, Universitätsklinikum Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Deutschland.
Hautarzt. 2021 Jan;72(1):6-13. doi: 10.1007/s00105-020-04736-7.
Ultraviolet (UV) radiation is the main risk factor for the development of melanocytic and nonmelanocytic skin cancer. UVA and UVB radiation are of particular importance in photocarcinogenesis. Depending on the wavelength, mechanisms of tumor initiation and promotion include direct DNA damage and proinflammatory processes. In recent years, the number of skin cancer cases in Germany has continuously increased. In addition to regular skin check-ups, use of suitable textile protection and sunscreens play a central role in the prevention of cancer development. As dermatologists, it is our task to regularly inform our patients about the consequences of excessive sun exposure and to adequately inform them about necessary protective devices.
紫外线（UV）辐射是黑素细胞性和非黑素细胞性皮肤癌发生的主要风险因素。UVA和UVB辐射在光致癌作用中尤为重要。根据波长不同，肿瘤起始和促进机制包括直接的DNA损伤和促炎过程。近年来，德国皮肤癌病例数量持续增加。除了定期皮肤检查外，使用合适的纺织品防护和防晒霜在预防癌症发生方面起着核心作用。作为皮肤科医生，我们的任务是定期告知患者过度日晒的后果，并充分告知他们必要的防护措施。
