在美国和加拿大，使用多功能护理液与过氧化氢的隐形眼镜佩戴者之间隐形眼镜并发症的发生率

Frequency of Contact Lens Complications Between Contact Lens Wearers Using Multipurpose Solutions Versus Hydrogen Peroxide in the United States and Canada.

作者信息

Tichenor Anna A, Cofield Stacey S, Gann Drew, Elder Marian, Ng Alison, Walsh Karen, Jones Lyndon W, Nichols Jason J

机构信息

Indiana University (A.A.T.), School of Optometry, Bloomington, IN; University of Alabama at Birmingham School of Optometry (S.S.C., J.J.N.), Birmingham, AL; EyeCare Associates (D.G.), Hueytown, Alabama; Centre for Ocular Research and Education (CORE) (M.E., A.N., K.W., L.W.J.), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada ; and Centre for Eye and Vision Research (LWJ), Hong Kong.

出版信息

Eye Contact Lens. 2021 May 1;47(5):277-282. doi: 10.1097/ICL.0000000000000761.

DOI:10.1097/ICL.0000000000000761

PMID:33290295

Abstract

OBJECTIVES

To retrospectively compare frequency of contact lens (CL) complications in soft CL users of hydrogen peroxide (H2O2) and multipurpose solutions (MPS).

METHODS

This was a multicenter, retrospective chart review of CL records from each patient's three most recent eye examinations at academic and private practices. Patients must have used the same solution type for at least 3 years. Univariate analyses were conducted using t tests, and chi-square or Fisher's exact test for categorical measures.

RESULTS

There were 1,137 patients included, with 670 (59%) using MPS and 467 (41%) H2O2. In total, 706 (62%) experienced at least one complication; 409 used MPS and 297 used H2O2. There was no difference in the proportion of patients experiencing at least one complication between MPS (61%) and H2O2 (64%) (P=0.38). Multipurpose solutions users were more likely to report discomfort compared with H2O2 users (P=0.04). Presumed microbial keratitis was experienced by 16 MPS and nine H2O2 users (P=0.60).

CONCLUSIONS

No significant differences were found in the frequency of CL complications between MPS and H2O2. H2O2 users were less likely to report discomfort and thus switching to a H2O2 system may be an alternative in CL users with discomfort.

摘要

目的

回顾性比较使用过氧化氢（H2O2）和多功能护理液（MPS）的软性隐形眼镜（CL）使用者中隐形眼镜并发症的发生率。

方法

这是一项多中心回顾性图表审查，回顾了学术机构和私人诊所中每位患者最近三次眼部检查的CL记录。患者必须使用同一种护理液类型至少3年。使用t检验进行单因素分析，对于分类变量采用卡方检验或Fisher精确检验。

结果

共纳入1137例患者，其中670例（59%）使用MPS，467例（41%）使用H2O2。总计706例（62%）经历了至少一种并发症；409例使用MPS，297例使用H2O2。MPS组（61%）和H2O2组（64%）中经历至少一种并发症的患者比例无差异（P = 0.38）。与H2O2使用者相比，MPS使用者更有可能报告不适（P = 0.04）。16例MPS使用者和9例H2O2使用者发生疑似微生物性角膜炎（P = 0.60）。