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GliMR:促进胶质瘤高级磁共振成像生物标志物的跨境合作。

GliMR: Cross-Border Collaborations to Promote Advanced MRI Biomarkers for Glioma.

作者信息

Clement Patricia, Booth Thomas, Borovečki Fran, Emblem Kyrre E, Figueiredo Patrícia, Hirschler Lydiane, Jančálek Radim, Keil Vera C, Maumet Camille, Özsunar Yelda, Pernet Cyril, Petr Jan, Pinto Joana, Smits Marion, Warnert Esther A H

机构信息

Ghent Institute for Metabolic and Functional Imaging (GIfMI), Ghent University, Ghent, Belgium.

School of Biomedical Engineering & Imaging Sciences, King's College London, St Thomas' Hospital, London, SE1 7EH UK.

出版信息

J Med Biol Eng. 2021;41(2):115-125. doi: 10.1007/s40846-020-00582-z. Epub 2020 Dec 3.

Abstract

PURPOSE

There is an annual incidence of 50,000 glioma cases in Europe. The optimal treatment strategy is highly personalised, depending on tumour type, grade, spatial localization, and the degree of tissue infiltration. In research settings, advanced magnetic resonance imaging (MRI) has shown great promise as a tool to inform personalised treatment decisions. However, the use of advanced MRI in clinical practice remains scarce due to the downstream effects of siloed glioma imaging research with limited representation of MRI specialists in established consortia; and the associated lack of available tools and expertise in clinical settings. These shortcomings delay the translation of scientific breakthroughs into novel treatment strategy. As a response we have developed the network "Glioma MR Imaging 2.0" (GliMR) which we present in this article.

METHODS

GliMR aims to build a pan-European and multidisciplinary network of experts and accelerate the use of advanced MRI in glioma beyond the current "state-of-the-art" in glioma imaging. The Action Glioma MR Imaging 2.0 (GliMR) was granted funding by the European Cooperation in Science and Technology (COST) in June 2019.

RESULTS

GliMR's first grant period ran from September 2019 to April 2020, during which several meetings were held and projects were initiated, such as reviewing the current knowledge on advanced MRI; developing a General Data Protection Regulation (GDPR) compliant consent form; and setting up the website.

CONCLUSION

The Action overcomes the pre-existing limitations of glioma research and is funded until September 2023. New members will be accepted during its entire duration.

摘要

目的

欧洲每年有50000例胶质瘤病例。最佳治疗策略高度个性化,取决于肿瘤类型、分级、空间定位和组织浸润程度。在研究环境中,先进的磁共振成像(MRI)作为一种为个性化治疗决策提供信息的工具显示出了巨大的前景。然而,由于胶质瘤成像研究的孤立性所带来的下游效应,以及既定联盟中MRI专家的代表性有限;加之临床环境中缺乏可用的工具和专业知识,先进MRI在临床实践中的应用仍然很少。这些缺点延缓了科学突破转化为新的治疗策略。作为回应,我们开发了“胶质瘤磁共振成像2.0”(GliMR)网络,本文将对此进行介绍。

方法

GliMR旨在建立一个泛欧洲的多学科专家网络,并加速先进MRI在胶质瘤中的应用,超越目前胶质瘤成像的“最新技术水平”。“胶质瘤磁共振成像2.0行动”(GliMR)于2019年6月获得欧洲科技合作组织(COST)的资助。

结果

GliMR的第一个资助期从2019年9月持续到2020年4月,在此期间举行了几次会议并启动了一些项目,如审查关于先进MRI的现有知识;制定符合通用数据保护条例(GDPR)的同意书;以及建立网站。

结论

该行动克服了胶质瘤研究先前存在的局限性,资助期至2023年9月。在其整个期间将接受新成员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bc1/7712600/8c45e9a35d36/40846_2020_582_Fig1_HTML.jpg

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