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Case Rep Pediatr. 2020 Nov 27;2020:2372843. doi: 10.1155/2020/2372843. eCollection 2020.
2
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An Pediatr (Barc). 2006 Feb;64(2):170-2. doi: 10.1157/13084179.
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MMWR Morb Mortal Wkly Rep. 2008 Feb 15;57(6):144-8.
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Recommendations for the prevention of Streptococcus pneumoniae infections in infants and children: use of 13-valent pneumococcal conjugate vaccine (PCV13) and pneumococcal polysaccharide vaccine (PPSV23).预防婴幼儿肺炎链球菌感染的建议：使用 13 价肺炎球菌结合疫苗（PCV13）和肺炎球菌多糖疫苗（PPSV23）。
Pediatrics. 2010 Jul;126(1):186-90. doi: 10.1542/peds.2010-1280. Epub 2010 May 24.
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J Clin Microbiol. 2017 Mar;55(3):724-734. doi: 10.1128/JCM.01778-16. Epub 2016 Nov 9.
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Vaccine. 2018 May 3;36(19):2559-2566. doi: 10.1016/j.vaccine.2018.04.010. Epub 2018 Apr 9.
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Invasive pneumococcal disease in young children before licensure of 13-valent pneumococcal conjugate vaccine - United States, 2007.13 价肺炎球菌结合疫苗获得许可前小儿侵袭性肺炎球菌病-美国，2007 年。
MMWR Morb Mortal Wkly Rep. 2010 Mar 12;59(9):253-7.
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Invasive disease potential of pneumococci before and after the 13-valent pneumococcal conjugate vaccine implementation in children.13价肺炎球菌结合疫苗在儿童中实施前后肺炎球菌的侵袭性疾病潜力
Vaccine. 2015 Nov 17;33(46):6178-85. doi: 10.1016/j.vaccine.2015.10.015. Epub 2015 Oct 21.
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Evolving picture of invasive pneumococcal disease in massachusetts children: a comparison of disease in 2007-2009 with earlier periods.马萨诸塞州儿童侵袭性肺炎球菌病的演变情况：2007-2009 年与早期疾病的比较。
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本文引用的文献

1
Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine Era: A Systematic Review.肺炎球菌疫苗时代侵袭性肺炎球菌疾病患儿免疫缺陷的患病率：一项系统评价
JAMA Pediatr. 2019 Nov 1;173(11):1084-1094. doi: 10.1001/jamapediatrics.2019.3203.
2
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.PCV13 时代后儿童侵袭性肺炎球菌病中与血清型转换和抗生素耐药相关的肺炎球菌谱系：一项国际全基因组测序研究。
Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10.
3
Preterm Children Have Higher Risk Than Full-term Children of Invasive Pneumococcal Disease During the First 2 Years of Life.早产儿在生命的头 2 年患侵袭性肺炎球菌病的风险高于足月儿。
Pediatr Infect Dis J. 2018 Jul;37(7):e195-e200. doi: 10.1097/INF.0000000000001989.
4
Rapid replacement by non-vaccine pneumococcal serotypes may mitigate the impact of the pneumococcal conjugate vaccine on nasopharyngeal bacterial ecology.快速被非疫苗型肺炎球菌血清型取代可能会减轻肺炎球菌结合疫苗对鼻咽部细菌生态的影响。
Sci Rep. 2017 Aug 15;7(1):8127. doi: 10.1038/s41598-017-08717-0.
5
Changes in the Nature and Severity of Invasive Pneumococcal Disease in Children Before and After the Seven-valent and Thirteen-valent Pneumococcal Conjugate Vaccine Programs in Calgary, Canada.加拿大卡尔加里七价和十三价肺炎球菌结合疫苗计划实施前后儿童侵袭性肺炎球菌疾病的性质和严重程度变化
Pediatr Infect Dis J. 2018 Jan;37(1):22-27. doi: 10.1097/INF.0000000000001709.
6
Surveillance of pneumococcal colonization and invasive pneumococcal disease reveals shift in prevalent carriage serotypes in Massachusetts' children to relatively low invasiveness.对肺炎球菌定植和侵袭性肺炎球菌疾病的监测显示，马萨诸塞州儿童中流行的携带血清型已转向侵袭性相对较低的类型。
Vaccine. 2017 Jul 13;35(32):4002-4009. doi: 10.1016/j.vaccine.2017.05.077. Epub 2017 Jun 20.
7
Serotype distribution of Streptococcus pneumoniae causing invasive disease in children in the post-PCV era: A systematic review and meta-analysis.肺炎球菌结合疫苗时代后引起儿童侵袭性疾病的肺炎链球菌血清型分布：一项系统评价和荟萃分析。
PLoS One. 2017 May 9;12(5):e0177113. doi: 10.1371/journal.pone.0177113. eCollection 2017.
8
Pneumococcal serotype distribution: A snapshot of recent data in pediatric and adult populations around the world.肺炎球菌血清型分布：全球儿童和成人人群近期数据概览。
Hum Vaccin Immunother. 2017 Jun 3;13(6):1-13. doi: 10.1080/21645515.2016.1277300. Epub 2017 Jan 26.
9
Emergence of Multidrug-Resistant Pneumococcal Serotype 35B among Children in the United States.美国儿童中多重耐药肺炎球菌35B血清型的出现。
J Clin Microbiol. 2017 Mar;55(3):724-734. doi: 10.1128/JCM.01778-16. Epub 2016 Nov 9.
10
The Effect of 13-Valent Pneumococcal Conjugate Vaccine on the Serotype Distribution and Antibiotic Resistance Profiles in Children With Invasive Pneumococcal Disease.13 价肺炎球菌结合疫苗对儿童侵袭性肺炎球菌病的血清型分布和抗生素耐药谱的影响。
J Pediatric Infect Dis Soc. 2017 Sep 1;6(3):253-259. doi: 10.1093/jpids/piw005.

美国农村地区由非疫苗血清型肺炎球菌引起的脑膜炎的出现。

Emergence of Meningitis Caused by Nonvaccine Serotypes of Pneumococcus in Rural United States.

作者信息

Marks Jessie, Bhoojhawon Guru V, Patrick Katherine D, Wood Kelly E

机构信息

Stead Family Department of Pediatrics, University of Iowa Stead Family Children's Hospital, 200 Hawkins Dr., Iowa City, Iowa 52242, USA.

出版信息

Case Rep Pediatr. 2020 Nov 27;2020:2372843. doi: 10.1155/2020/2372843. eCollection 2020.

DOI:10.1155/2020/2372843
PMID:33294245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7718068/
Abstract

Pneumococcal conjugate vaccines have decreased the rates of invasive pneumococcal disease (IPD) in children. Since vaccine introduction, however, rates of infection due to nonvaccine serotypes have increased. We now describe 3 meningitis cases due to the nonvaccine serotypes 35B and 11A from rural United States.

摘要

肺炎球菌结合疫苗降低了儿童侵袭性肺炎球菌疾病（IPD）的发病率。然而，自疫苗引入以来，非疫苗血清型引起的感染率有所上升。我们现在描述3例来自美国农村地区、由非疫苗血清型35B和11A引起的脑膜炎病例。