Savary Dominique, Lesimple Arnaud, Beloncle François, Morin François, Templier François, Broc Alexandre, Brochard Laurent, Richard Jean-Christophe, Mercat Alain
Emergency Department, University Hospital of Angers, 4, Rue Larrey, 49933, Angers Cedex 9, France.
Inserm, EHESP, University of Rennes, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, 49000, Angers, France.
Ann Intensive Care. 2020 Dec 9;10(1):166. doi: 10.1186/s13613-020-00782-5.
Intensive Care Units (ICU) have sometimes been overwhelmed by the surge of COVID-19 patients. Extending ICU capacity can be limited by the lack of air and oxygen pressure sources available. Transport ventilators requiring only one O source may be used in such places.
To evaluate the performances of four transport ventilators and an ICU ventilator in simulated severe respiratory conditions.
Two pneumatic transport ventilators, (Oxylog 3000, Draeger; Osiris 3, Air Liquide Medical Systems), two turbine transport ventilators (Elisee 350, ResMed; Monnal T60, Air Liquide Medical Systems) and an ICU ventilator (Engström Carestation-GE Healthcare) were evaluated on a Michigan test lung. We tested each ventilator with different set volumes (Vt = 350, 450, 550 ml) and compliances (20 or 50 ml/cmHO) and a resistance of 15 cmHO/l/s based on values described in COVID-19 Acute Respiratory Distress Syndrome. Volume error (percentage of Vt) with P of 4 cmHO and trigger delay during assist-control ventilation simulating spontaneous breathing activity with P of 4 cmHO and 8 cmHO were measured.
Grouping all conditions, the volume error was 2.9 ± 2.2% for Engström Carestation; 3.6 ± 3.9% for Osiris 3; 2.5 ± 2.1% for Oxylog 3000; 5.4 ± 2.7% for Monnal T60 and 8.8 ± 4.8% for Elisee 350. Grouping all conditions (P of 4 cmHO and 8 cmHO), trigger delay was 50 ± 11 ms, 71 ± 8 ms, 132 ± 22 ms, 60 ± 12 and 67 ± 6 ms for Engström Carestation, Osiris 3, Oxylog 3000, Monnal T60 and Elisee 350, respectively.
In surge situations such as COVID-19 pandemic, transport ventilators may be used to accurately control delivered volumes in locations, where only oxygen pressure supply is available. Performances regarding triggering function are acceptable for three out of the four transport ventilators tested.
重症监护病房(ICU)有时会因新冠病毒疾病(COVID-19)患者的激增而不堪重负。由于可用的空气和氧气压力源不足,扩大ICU容量可能会受到限制。在这些地方可使用仅需一种氧气源的转运呼吸机。
评估四种转运呼吸机和一种ICU呼吸机在模拟严重呼吸状况下的性能。
在密歇根测试肺上评估了两台气动转运呼吸机(Oxylog 3000,德尔格公司;Osiris 3,液化空气医疗系统公司)、两台涡轮转运呼吸机(Elisee 350,瑞思迈公司;Monnal T60,液化空气医疗系统公司)和一台ICU呼吸机(Engström Carestation,通用电气医疗集团)。我们根据COVID-19急性呼吸窘迫综合征中描述的值,用不同的设定容积(Vt = 350、450、550毫升)和顺应性(20或50毫升/厘米水柱)以及15厘米水柱/升/秒的阻力对每台呼吸机进行测试。测量了在4厘米水柱的气道压力下的容积误差(占Vt的百分比)以及在辅助控制通气期间模拟4厘米水柱和8厘米水柱的自主呼吸活动时的触发延迟。
综合所有情况,Engström Carestation的容积误差为2.9±2.2%;Osiris 3为3.6±3.9%;Oxylog 3000为2.5±2.1%;Monnal T60为5.4±2.7%;Elisee 350为8.8±4.8%。综合所有情况(4厘米水柱和8厘米水柱的气道压力),Engström Carestation、Osiris 3、Oxylog 3000、Monnal T60和Elisee 350的触发延迟分别为50±11毫秒、71±8毫秒、132±22毫秒、60±12毫秒和67±6毫秒。
在诸如COVID-19大流行这样的紧急情况下,转运呼吸机可用于仅提供氧气压力的场所,以精确控制输送的容积。所测试的四种转运呼吸机中有三种在触发功能方面的性能是可接受的。