Baboi Loredana, Subtil Fabien, Guérin Claude
Medical ICU, Lyon University Hospital, Lyon, France.
Biostatistic Department, Lyon University Hospital, Lyon, France;; University of Lyon, Lyon, France;; Biometry and Evolutionary Biology Laboratory, CNRS 5558, Villeurbanne, France.
J Thorac Dis. 2016 Dec;8(12):3639-3647. doi: 10.21037/jtd.2016.12.64.
Turbine-powered ventilators are not only designed for long-term ventilation at home but also for hospital use. It is important to verify their capabilities in delivering fraction of oxygen in air (FO) and tidal volume (V).
We assessed the FO accuracy and the V delivery in four home care ventilators (HCV) on the bench. The four HCV were Astral 150, Elisée 150, Monnal T50 and Trilogy 200 HCV, which were connected to a lung model (ASL 5000). For assessing FO accuracy, lung model was set to mimic an obstructive lung and HCV were set in volume controlled mode (VC). They supplied with air, 3 or 15 L/min oxygen and FO was measured by using a ventilator tester (Citrex H4). For the V accuracy, the lung model was set in a way to mimic three adult configurations (normal, obstructive, or restrictive respiratory disorder) and one pediatric configuration. Each HCV was set in VC. Two V (300 and 500 mL) in adult lung configuration and one 50 mL V in pediatric lung configuration, at two positive end expiratory pressures 5 and 10 cmHO, were tested. V accuracy was measured as volume error (the relative difference between set and measured V). Statistical analysis was performed by suing one-factor ANOVA with a Bonferroni correction for multiple tests.
For Astral 150, Elisée 150, Monnal T50 and Trilogy 200, FO averaged 99.2%, 93.7%, 86.3%, and 62.1%, respectively, at 15 L/min oxygen supplementation rate (P<0.001). Volume error was 0.5%±0%, -38%±0%, -9%±0%, -29%±0% and -36%±0% for pediatric lung condition (P<0.001). In adult lung configurations, Monnal T50 systematically over delivered V and Trilogy 150 was sensitive to lung configuration when V was set to 300 mL at either positive end-expiratory pressure (PEEP).
HCV are different in terms of FO efficiency and V delivery.
涡轮动力呼吸机不仅设计用于家庭长期通气,也用于医院。验证其输送空气中氧气分数(FO)和潮气量(V)的能力很重要。
我们在实验台上评估了四款家用护理呼吸机(HCV)的FO准确性和V输送情况。这四款HCV分别是Astral 150、Elisée 150、Monnal T50和Trilogy 200 HCV,它们连接到一个肺模型(ASL 5000)。为评估FO准确性,将肺模型设置为模拟阻塞性肺,HCV设置为容量控制模式(VC)。向其供应空气、3或15 L/min的氧气,并用呼吸机测试仪(Citrex H4)测量FO。对于V准确性,将肺模型设置为模拟三种成人配置(正常、阻塞性或限制性呼吸障碍)和一种儿科配置。每个HCV都设置为VC。在成人肺配置中测试两个V(300和500 mL),在儿科肺配置中测试一个50 mL的V,在两个呼气末正压5和10 cmHO下进行测试。V准确性以容积误差(设定V与测量V之间的相对差异)来衡量。通过单因素方差分析并采用Bonferroni校正进行多重检验来进行统计分析。
对于Astral 150、Elisée 150、Monnal T50和Trilogy 200,在15 L/min氧气补充率下,FO平均分别为99.2%、93.7%、86.3%和62.1%(P<0.001)。儿科肺状况下的容积误差分别为0.5%±0%、-38%±0%、-9%±0%、-29%±0%和-36%±0%(P<0.001)。在成人肺配置中,当在任一呼气末正压(PEEP)下将V设置为300 mL时,Monnal T50系统性地过度输送V,而Trilogy 150对肺配置敏感。
HCV在FO效率和V输送方面存在差异。