Henghold William B
Dermatology Service, Tripler Army Medical Center Hawaii, 1 Jarrett White Road, HI 96859-5000, USA.
Dermatol Clin. 2004 Jul;22(3):257-62, v. doi: 10.1016/j.det.2004.03.004.
The ideal biologic warfare agent is lethal, easy, and inexpensive to produce in large quantities, stable in aerosol for/with the ability to be dispersed over wide areas, has no effective treatment or vaccine, and is communicable from person to person. With the exception of the last characteristic, the biologic toxins (ricin, staphylococcal enterotoxin B, T-2 mycotoxin, and botulinum) possess all the properties mentioned. This article will discuss the first three biologic toxins, with an emphasis on particular points of interest to the dermatologist. Botulinum toxin will be covered in another article.
理想的生物战剂应具备致命性,易于大量生产且成本低廉,在气溶胶中稳定且具备在广阔区域散布的能力,没有有效的治疗方法或疫苗,并且能够人际传播。除了最后一个特性外,生物毒素(蓖麻毒素、葡萄球菌肠毒素B、T-2霉菌毒素和肉毒杆菌毒素)具备上述所有特性。本文将讨论前三种生物毒素,重点关注皮肤科医生感兴趣的特定要点。肉毒杆菌毒素将在另一篇文章中论述。