加强实验室诊断能力，支持乌干达的癌症护理。
Strengthening Laboratory Diagnostic Capacity to Support Cancer Care in Uganda.
机构信息
Uganda Cancer Institute, Kampala, Uganda.
Department of Pathology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
出版信息
Am J Clin Pathol. 2021 Jul 6;156(2):205-213. doi: 10.1093/ajcp/aqaa218.
OBJECTIVES
An accurate cancer diagnosis is critical to providing quality care to patients with cancer. We describe the results of a laboratory improvement process that started in 2017 to improve access to cancer diagnostics at the Uganda Cancer Institute (UCI). The overall objective of the project was to build capacity for the provision of quality and timely laboratory diagnostics to support cancer care in Uganda.
METHODS
A phased multistep approach was used to improve laboratory capacity, including staff training, additional staff recruitment, equipment overhaul, and optimization of the supply chain.
RESULTS
The program led to the establishment of a pathology laboratory that handled 5,700 tissue diagnoses in 2019. Immunohistochemistry services are now offered routinely. Turnaround time for histopathology has also reduced from an average of 7 to 14 days to 5.4 days. The main clinical laboratory has also increased both the test volume and the test capacity, with the additional establishment of a molecular diagnostics laboratory.
CONCLUSIONS
Our project shows a pathway to the improvement of laboratory diagnostic capacity in cancer care centers in sub-Saharan Africa (SSA). Improved laboratory diagnostic capacity is critical to improving cancer care in SSA and more rational use of targeted therapies.
目的
准确的癌症诊断对于为癌症患者提供高质量的护理至关重要。我们描述了始于 2017 年的一个实验室改进过程的结果，该过程旨在提高乌干达癌症研究所（UCI）癌症诊断的可及性。该项目的总体目标是为提供优质和及时的实验室诊断建立能力，以支持乌干达的癌症护理。
方法
采用分阶段的多步骤方法来提高实验室能力，包括员工培训、额外的员工招聘、设备检修以及优化供应链。
结果
该计划促成了一个病理实验室的建立，该实验室在 2019 年处理了 5700 例组织诊断。现在常规提供免疫组织化学服务。组织病理学的周转时间也从平均 7 至 14 天缩短至 5.4 天。主要临床实验室也增加了检测量和检测能力，还额外建立了一个分子诊断实验室。
结论
我们的项目展示了撒哈拉以南非洲（SSA）癌症护理中心改善实验室诊断能力的途径。提高实验室诊断能力对于改善 SSA 的癌症护理和更合理地使用靶向治疗至关重要。
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