Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Clin Immunol. 2021 Jan;222:108646. doi: 10.1016/j.clim.2020.108646. Epub 2020 Dec 7.
Kawasaki disease (KD) is an inflammatory syndrome which is generally observed among children. Considering the significant number of COVID-19-positive children presenting with the manifestations of typical/atypical KD, it has been mentioned as a possible complication of COVID-19 infection among the children. However, many of the reported cases do not completely fill the clinical diagnostic criteria, which has made some researchers use the term "Kawasaki-like disease" instead of KD for this state. The current manuscript aims to review the key studies in the field, address the ongoing conflict, and indicate the objective requirements of the further studies.
川崎病（KD）是一种常见于儿童的炎症综合征。鉴于 COVID-19 阳性儿童中有相当数量的患者出现典型/非典型 KD 的表现，因此有人认为 COVID-19 感染可能是儿童的一种并发症。然而，许多报道的病例并不完全符合临床诊断标准，这使得一些研究人员使用“川崎样疾病”一词来代替 KD 来描述这种状态。本文旨在回顾该领域的关键研究，解决当前的争议，并指出进一步研究的客观要求。
