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慢性病患者的应急管理:随机对照试验的系统评价与荟萃分析

Contingency management for individuals with chronic health conditions: A systematic review and meta-analysis of randomized controlled trials.

作者信息

Ellis Jennifer D, Struble Cara A, Fodor Marina C, Cairncross Molly, Lundahl Leslie H, Ledgerwood David M

机构信息

Department of Psychiatry & Behavioral Neurosciences, Wayne State University, USA; Department of Psychiatry & Behavioral Sciences, Johns Hopkins University, USA.

Department of Psychiatry & Behavioral Neurosciences, Wayne State University, USA.

出版信息

Behav Res Ther. 2021 Jan;136:103781. doi: 10.1016/j.brat.2020.103781. Epub 2020 Nov 30.

Abstract

BACKGROUND

Contingency management (CM) interventions involve providing reinforcement for engaging in a desired behavior, and have been shown to increase treatment adherence and promote abstinence in the treatment of substance use disorders. This review was conducted to systematically review the literature on the effectiveness of CM when applied to a range of medical conditions outside of substance use disorders.

METHOD

The authors identified a total of 24 randomized studies examining the effects of CM on four outcomes: weight change, physical activity, medication/device adherence, and viral load that were included in the qualitative summary, and 20 studies included in the meta-analysis.

RESULTS

CM was associated with positive outcomes for physical activity and medication/device adherence compared to control conditions. Findings with weight loss and viral load were more mixed, and evidence for publication bias was found for both outcomes. The effects of CM tend to dissipate when the contingency is removed. Heterogeneity was observed across most outcomes.

LIMITATIONS AND CONCLUSIONS

This review provides preliminary support for the use of CM in increasing physical activity and improving adherence to medication for chronic health conditions while reinforcement is ongoing. Future studies should examine potential moderators and identify strategies to maintain these changes over time.

摘要

背景

应急管理(CM)干预措施包括对参与期望行为给予强化,并且已证明在物质使用障碍治疗中可提高治疗依从性并促进戒断。进行本次综述是为了系统回顾关于CM应用于物质使用障碍以外一系列医疗状况时有效性的文献。

方法

作者共确定了24项随机研究,这些研究考察了CM对四个结果的影响:体重变化、身体活动、药物/器械依从性以及病毒载量,这些研究被纳入定性总结,20项研究被纳入荟萃分析。

结果

与对照条件相比,CM与身体活动和药物/器械依从性的积极结果相关。体重减轻和病毒载量方面的研究结果更为复杂,并且在这两个结果中均发现了发表偏倚的证据。当应急情况消除时,CM的效果往往会消失。在大多数结果中观察到了异质性。

局限性与结论

本综述为在强化持续进行时使用CM增加身体活动以及改善慢性健康状况下的药物依从性提供了初步支持。未来的研究应考察潜在的调节因素,并确定随着时间推移维持这些变化的策略。

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