Sarabaegi Masoumeh, Roushani Mahmoud, Hosseini Hadi
Department of Chemistry, Ilam University, PO. Box 69315-516, Ilam, Iran.
Department of Chemistry, Ilam University, PO. Box 69315-516, Ilam, Iran.
Talanta. 2021 Feb 1;223(Pt 1):121700. doi: 10.1016/j.talanta.2020.121700. Epub 2020 Sep 24.
The design of hollow mesoporous carbon-based materials has attracted tremendous attention, due to their sizeable intrinsic cavity to load specific chemical and unique physical/chemical properties in various applications. Herein, we have established an effective strategy for the preparation of novel hollow carbon nanocapsules-based nitrogen-doped carbon nanofibers (CNCNF) with rosary-like structure. By embedding ultrafine hollow carbon nanocapsules into electrospun polyacrylonitrile (PAN) skeleton, the as-designed composite CNFs were carbonized into hierarchical porous CNFs, consisted of interconnected nitrogen-doped hollow carbon nanocapsules. Due to its individual structural properties and unique chemical composition, the performance of CNCNF was evaluated in aptasensor application via the detection of Pseudomonas aeruginosa (PA). Under optimized conditions, the aptasensor based on CNCNF has a detection limit of 1 CFU⋅mL and a linear range from 10 CFU ⋅mL to 10 CFU ⋅mL (n = 3). Moreover, the designed aptasensor possesses high sensivity, high selectivity, low detection limit, and high reproducibility. These studies showed that the CNCNF material offers a wide variety of enhanced electrochemical features as an electrode material for aptasensor application.
中空介孔碳基材料的设计因其具有较大的固有空腔以负载特定化学物质以及在各种应用中独特的物理/化学性质而备受关注。在此，我们建立了一种有效的策略来制备具有念珠状结构的新型中空碳纳米胶囊基氮掺杂碳纳米纤维（CNCNF）。通过将超细中空碳纳米胶囊嵌入静电纺丝聚丙烯腈（PAN）骨架中，将设计的复合碳纳米纤维碳化成分层多孔碳纳米纤维，其由相互连接的氮掺杂中空碳纳米胶囊组成。由于其独特的结构性质和化学组成，通过检测铜绿假单胞菌（PA）在适体传感器应用中评估了CNCNF的性能。在优化条件下，基于CNCNF的适体传感器检测限为1 CFU⋅mL，线性范围为10 CFU ⋅mL至10 CFU ⋅mL（n = 3）。此外，所设计的适体传感器具有高灵敏度、高选择性、低检测限和高重现性。这些研究表明，CNCNF材料作为适体传感器应用的电极材料具有多种增强的电化学特性。
