Suppr超能文献

原发性甲状旁腺功能亢进症中的高钙血症:复发性急性胰腺炎的罕见病因。

Hypercalcaemia in primary hyperparathyroidism: a rare cause of recurrent acute pancreatitis.

机构信息

Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India.

Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India

出版信息

BMJ Case Rep. 2020 Dec 10;13(12):e237875. doi: 10.1136/bcr-2020-237875.

Abstract

Hyperparathyroidism leading to hypercalcaemia is a rare cause of acute pancreatitis with debatable association. The diagnosis of hyperparathyroidism is frequently overlooked or delayed as symptoms are non-specific and serum calcium is not routinely measured in acute pancreatitis. Early diagnosis and treatment of hyperparathyroidism may reduce the chances of complications. We report a 35-year-old woman, who was admitted with recurrent episodes of acute pancreatitis. She was previously diagnosed with gall-stone induced acute pancreatitis, had undergone laparoscopic cholecystectomy, but the recurrence of acute pancreatitis suggested an alternative aetiology and provoked extensive investigations. Serum calcium was found to be elevated. No additional risk factor for pancreatitis was found. Further workup revealed primary hyperparathyroidism, which was due to a functioning parathyroid adenoma. She has undergone parathyroidectomy followed by an uneventful recovery. She subsequently conceived and is now in her first trimester, without any recurrence of acute pancreatitis since her surgery.

摘要

甲状旁腺功能亢进导致高钙血症是急性胰腺炎的罕见病因,其相关性存在争议。甲状旁腺功能亢进的诊断经常被忽视或延迟,因为症状是非特异性的,而且在急性胰腺炎中通常不常规测量血清钙。早期诊断和治疗甲状旁腺功能亢进症可能会降低并发症的发生几率。我们报告了一位 35 岁的女性,她因反复发作的急性胰腺炎入院。她之前被诊断为胆石性诱导的急性胰腺炎,曾行腹腔镜胆囊切除术,但急性胰腺炎的复发提示存在其他病因,并引发了广泛的检查。发现血清钙升高。未发现胰腺炎的其他危险因素。进一步的检查显示为原发性甲状旁腺功能亢进症,是由于甲状旁腺腺瘤功能亢进所致。她已接受甲状旁腺切除术,术后恢复顺利。随后她怀孕了,现在处于孕早期,自手术后没有再发生急性胰腺炎。

相似文献

1
Hypercalcaemia in primary hyperparathyroidism: a rare cause of recurrent acute pancreatitis.
BMJ Case Rep. 2020 Dec 10;13(12):e237875. doi: 10.1136/bcr-2020-237875.
2
Acute pancreatitis associated with primary hyperparathyroidism.
Updates Surg. 2011 Jun;63(2):135-8. doi: 10.1007/s13304-011-0048-9. Epub 2011 Feb 1.
4
Acute pancreatitis and refractory hypercalcemia in the third trimester caused by parathyroid carcinoma.
BMC Pregnancy Childbirth. 2024 Jul 17;24(1):483. doi: 10.1186/s12884-024-06636-3.
5
Hyperparathyroidism during pregnancy. Is it a diagnostic and therapeutic challenge?
Cir Cir. 2019;87(S1):62-67. doi: 10.24875/CIRU.19000796.
6
Primary hyperparathyroidism presenting as severe hypercalcemia with acute pancreatitis in pregnancy.
Gynecol Endocrinol. 2020 May;36(5):469-472. doi: 10.1080/09513590.2019.1698028. Epub 2019 Dec 3.
7
Primary hyperparathyroidism in pregnancy leading to hypercalcaemic crisis and uraemic encephalopathy.
BMJ Case Rep. 2015 Mar 27;2015:bcr2014208829. doi: 10.1136/bcr-2014-208829.
9
Recurrent acute pancreatitis as the first and sole presentation of undiagnosed primary hyperparathyroidism.
Ann R Coll Surg Engl. 2010 Mar;92(2):W29-31. doi: 10.1308/147870810X476746.
10
Acute pancreatitis and parathyroid carcinoma: a case report and literature review.
Eur Rev Med Pharmacol Sci. 2021 Oct;25(19):5972-5977. doi: 10.26355/eurrev_202110_26874.

本文引用的文献

1
Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets.
Int Sch Res Notices. 2016 Sep 27;2016:7294274. doi: 10.1155/2016/7294274. eCollection 2016.
2
The association of primary hyperparathyroidism with pancreatitis.
J Clin Gastroenterol. 2012 Sep;46(8):656-61. doi: 10.1097/MCG.0b013e31825c446c.
3
Primary hyperparathyroidism presenting as recurrent acute pancreatitis: A case report and review of literature.
Indian J Endocrinol Metab. 2011 Jan;15(1):54-6. doi: 10.4103/2230-8210.77588.
4
[Acute pancreatitis and primary hyperparathyroidism: a multicentric study by the Francophone Association of Endocrine Surgeons].
J Chir (Paris). 2009 Jun;146(3):270-4. doi: 10.1016/j.jchir.2009.06.016. Epub 2009 Aug 18.
5
Acute pancreatitis associated with hypercalcemia. A report of two cases.
Rev Esp Enferm Dig. 2009 Jan;101(1):65-9. doi: 10.4321/s1130-01082009000100009.
6
Does hyperparathyroidism cause pancreatitis? A South Indian experience and a review of published work.
ANZ J Surg. 2006 Aug;76(8):740-4. doi: 10.1111/j.1445-2197.2006.03845.x.
7
Primary hyperparathyroidism: new concepts in clinical, densitometric and biochemical features.
J Intern Med. 2005 Jan;257(1):6-17. doi: 10.1111/j.1365-2796.2004.01422.x.
8
Pancreatitis in patients with primary hyperparathyroidism.
Indian J Gastroenterol. 2003 Nov-Dec;22(6):224-5.
9
Oral alendronate increases bone mineral density in postmenopausal women with primary hyperparathyroidism.
J Clin Endocrinol Metab. 2003 Feb;88(2):581-7. doi: 10.1210/jc.2002-020890.
10
The effects of vitamin D insufficiency in patients with primary hyperparathyroidism.
Am J Med. 1999 Dec;107(6):561-7. doi: 10.1016/s0002-9343(99)00294-6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验