Siegel Diane T, Ertel Monica K, Patnaik Jennifer L, Awadallah Nida S, Capitena Young Cara E, Seibold Leonard K, Kahook Malik Y
Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, The University of Colorado School of Medicine, Aurora, Colorado, USA.
Department of Family Medicine, The University of Colorado School of Medicine, Aurora, Colorado, USA.
J Curr Glaucoma Pract. 2020 May-Aug;14(2):57-60. doi: 10.5005/jp-journals-10078-1282.
The goal of this study was to measure acute ocular effects in patients undergoing routine sphenopalatine ganglion (SPG) nerve block for headache. Projections from the SPG influence blood flow to the eye which may influence intraocular pressure (IOP). There are limited animal and human studies investigating the relationship between the SPG and its effect on the eye.
This was a single-site, investigator-initiated, single-visit, prospective study. Participants were aged 18-85 years old who had consented to SPG nerve block for headache. The primary outcome measures were change in near visual acuity (NVA) and IOP pre-procedure to immediately post-procedure. Additional data collected included pupil diameter and presence of any ocular or visual complaints.
A total of 13 patients were enrolled in the study. Average pre-procedure IOP was 14.2 mm Hg [standard deviation (SD) 3.8] in the right eye and 13.7 mm Hg (SD 3.2) in the left eye. Average post-procedure IOP was 14.8 mm Hg (SD 3.8) in the right eye and 14.2 mm Hg (SD 2.9) in the left eye. Neither the right nor left eye experienced a statistically significant change in IOP after SPG block. There were no statistically significant changes in average NVA or pupil diameter in either eye. There were no adverse events.
This pilot study suggests no significant acute changes in IOP or other ocular parameters after SPG block for headache disorders and supports the fact that the procedure is safe as it relates to ocular health. The ocular effects of SPG blockade merit further study in a larger cohort of patients.
Siegel DT, Ertel MK, Patnaik JL, Acute Ocular Effects of Sphenopalatine Ganglion Nerve Block. J Curr Glaucoma Pract 2020;14(2):57-60.
本研究的目的是测量因头痛接受常规蝶腭神经节(SPG)神经阻滞的患者的急性眼部效应。SPG的投射影响眼部血流,这可能会影响眼内压(IOP)。关于SPG及其对眼睛影响之间关系的动物和人体研究有限。
这是一项单中心、研究者发起的、单次就诊的前瞻性研究。参与者年龄在18 - 85岁之间,已同意因头痛接受SPG神经阻滞。主要结局指标是术前至术后即刻近视力(NVA)和IOP的变化。收集的其他数据包括瞳孔直径以及任何眼部或视觉不适的情况。
共有13名患者纳入研究。术前右眼平均IOP为14.2毫米汞柱[标准差(SD)3.8],左眼为13.7毫米汞柱(SD 3.2)。术后右眼平均IOP为14.8毫米汞柱(SD 3.8),左眼为14.2毫米汞柱(SD 2.9)。SPG阻滞后,右眼和左眼的IOP均未出现统计学上的显著变化。任一眼的平均NVA或瞳孔直径均无统计学上的显著变化。无不良事件发生。
这项初步研究表明,头痛疾病患者接受SPG阻滞后,IOP或其他眼部参数无明显急性变化,并支持该操作在眼部健康方面是安全的这一事实。SPG阻滞的眼部效应值得在更大规模的患者队列中进一步研究。
Siegel DT, Ertel MK, Patnaik JL, 蝶腭神经节神经阻滞的急性眼部效应。《当代青光眼实践杂志》2020年;14(2):57 - 60。