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通过实现每日下午的目标来延长中风患者的预期寿命。

Prolonged Life Expectancy for Those Dying of Stroke by Achieving the Daily PM Targets.

作者信息

Ruan Zengliang, Qi Jinlei, Yin Peng, Qian Zhengmin Min, Liu Jiangmei, Liu Yunning, Yang Yin, Li Huan, Zhang Shiyu, Howard Steven W, Lin Hualiang, Wang Lijun

机构信息

Department of Epidemiology School of Public Health Sun Yat-Sen University Guangzhou 510080 China.

National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and Prevention Beijing 100050 China.

出版信息

Glob Chall. 2020 Oct 13;4(12):2000048. doi: 10.1002/gch2.202000048. eCollection 2020 Dec.

Abstract

This time-series study collects data on stroke-related mortality, years of life lost (YLL), air pollution, and meteorological conditions in 96 Chinese cities from 2013 to 2016 and proposes a three-stage strategy to generate the national and regional estimations of avoidable YLL, gains in life expectancy and stroke-related population attributable fraction by postulating that the daily fine particulate matter (PM) has been kept under certain standards. A total of 1 318 911 stroke deaths are analyzed. Each 10 µg m increment in PM at lag is associated with a city-mean increase of 0.31 (95% CI: 0.19, 0.44) years of life lost from stroke. A number of 914.11 (95% CI: 538.28, 1288.94) years of city-mean life lost from stoke could be avoided by attaining the WHO's Air Quality Guidelines (AQG) (25 µg m). Moreover, by applying the AQG standard, 0.11 (0.08, 0.15) years of life lost might be prevented for each death, and about 0.91% (95% CI: 0.62%, 1.19%) of the total years of life lost from stroke might be explained by the daily excess PM exposure. This study indicates that stroke patients can have a longer life expectancy if stricter PM standards are put in place, especially ischemic stroke patients.

摘要

这项时间序列研究收集了2013年至2016年中国96个城市中风相关死亡率、寿命损失年数(YLL)、空气污染和气象条件的数据,并提出了一个三阶段策略,通过假设每日细颗粒物(PM)一直保持在特定标准以下,来生成全国和区域可避免的YLL、预期寿命增加以及中风相关人群归因分数的估计值。总共分析了1318911例中风死亡病例。滞后时PM每增加10 μg/m³,与中风导致的城市平均寿命损失增加0.31年(95%置信区间:0.19,0.44)相关。通过达到世界卫生组织的空气质量指南(AQG)(25 μg/m³),可以避免914.11年(95%置信区间:538.28,1288.94)的城市平均中风寿命损失。此外,应用AQG标准,每例死亡可能预防0.11年(0.08,0.15)的寿命损失,中风导致的总寿命损失中约0.91%(95%置信区间:0.62%,1.19%)可由每日过量的PM暴露解释。这项研究表明,如果实施更严格的PM标准,中风患者可以有更长的预期寿命,尤其是缺血性中风患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad73/7713556/5fa7e320a432/GCH2-4-2000048-g001.jpg

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