Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal and Infantile Sciences (DINOGMI), University of Genoa, Genoa, Italy -
Italian Multiple Sclerosis Society Research Foundation (FISM), Genoa, Italy.
Eur J Phys Rehabil Med. 2021 Aug;57(4):520-526. doi: 10.23736/S1973-9087.20.06446-1. Epub 2020 Dec 11.
Impaired upper limb functionality and dexterity are common in people with multiple sclerosis (PwMS) and lead to increased dependency and reduced quality of life.
The aim of this study was to compare the ability of the Manual Abilites Measure 36 (MAM-36) and the ABILHAND questionnaire to recognize an involvement of the upper limbs in PwMS, and to compare their results with those of other patient reported outcomes (PRO) evaluating disability, functional independence, symptoms of anxiety and depression, fatigue and quality of life.
The study design was observational.
The setting of the study was outpatient.
The study population included fifty-one PwMS (mean age of 56.31 years, age range of 33-82 years, 72.5% of patients were females).
For each patient were collected MAM-36, ABILHAND questionnaire, expanded disability status scale (EDSS), Functional Independence measure (FIM), Hospital Anxiety and Depression Scale (HADS), Modified Fatigue Impact Scale (MFIS) and Life Satisfaction Index (LSI).
A strong correlation between MAM-36 and the ABILHAND questionnaire (Spearman r: 0.79; P<0.0001) were found. We obtained a significant correlation between MAM-36 and EDSS (Spearman r: -0.5; P=0.0002), FIM (Spearman r: 0.55; P<0.0001); we did not observe a correlation with MFIS (Spearman r: -0.33; P=0.02); moreover we found a similar trend between ABILHAND and EDSS (Spearman r: -0.47; P=0.0005), FIM (Spearman r: 0.61; P<0.0001), MFIS (Spearman r: -0.41; P=0.002).
In PwMS the assessment of upper limbs is fundamental since it closely related to the level of disability of the person. Both MAM-36 and ABILHAND Questionnaire are equally able to detect upper limb dysfunctions in PwMS.
Both MAM-36 and ABILHAND can be used for upper limbs evaluation, within a multidimensional approach that seems to be the best way to evaluate PwMS.
上肢功能和灵活性受损在多发性硬化症患者（PwMS）中很常见，这导致他们的依赖性增加，生活质量下降。
本研究旨在比较手动能力测量 36 项（MAM-36）和 ABILHAND 问卷识别 PwMS 上肢受累的能力，并将其结果与评估残疾、功能独立性、焦虑和抑郁症状、疲劳和生活质量的其他患者报告结局（PRO）进行比较。
研究设计为观察性。
研究地点为门诊。
研究人群包括 51 名 PwMS（平均年龄 56.31 岁，年龄范围 33-82 岁，72.5%的患者为女性）。
为每位患者收集 MAM-36、ABILHAND 问卷、扩展残疾状况量表（EDSS）、功能独立性测量（FIM）、医院焦虑和抑郁量表（HADS）、修正疲劳影响量表（MFIS）和生活满意度指数（LSI）。
MAM-36 和 ABILHAND 问卷之间存在很强的相关性（Spearman r：0.79；P<0.0001）。我们发现 MAM-36 与 EDSS（Spearman r：-0.5；P=0.0002）、FIM（Spearman r：0.55；P<0.0001）之间存在显著相关性；我们没有发现与 MFIS（Spearman r：-0.33；P=0.02）之间存在相关性；此外，我们发现 ABILHAND 与 EDSS（Spearman r：-0.47；P=0.0005）、FIM（Spearman r：0.61；P<0.0001）、MFIS（Spearman r：-0.41；P=0.002）之间存在类似的趋势。
在 PwMS 中，上肢的评估至关重要，因为它与患者的残疾程度密切相关。MAM-36 和 ABILHAND 问卷在检测 PwMS 患者上肢功能障碍方面同样有效。
MAM-36 和 ABILHAND 均可用于上肢评估，在多维方法中，这似乎是评估 PwMS 的最佳方法。
