Department of Plant Pathology and Microbiology, Texas A & M University, College Station, Texas, 77843, USA.
Department of Biochemistry and Biophysics, Texas A & M University, College Station, Texas, 77843, USA.
J Integr Plant Biol. 2021 Jan;63(1):79-101. doi: 10.1111/jipb.13051.
As sessile organisms, plants are exposed to pathogen invasions and environmental fluctuations. To overcome the challenges of their surroundings, plants acquire the potential to sense endogenous and exogenous cues, resulting in their adaptability. Hence, plants have evolved a large collection of plasma membrane-resident receptors, including RECEPTOR-LIKE KINASEs (RLKs) and RECEPTOR-LIKE PROTEINs (RLPs) to perceive those signals and regulate plant growth, development, and immunity. The ability of RLKs and RLPs to recognize distinct ligands relies on diverse categories of extracellular domains evolved. Co-regulatory receptors are often required to associate with RLKs and RLPs to facilitate cellular signal transduction. RECEPTOR-LIKE CYTOPLASMIC KINASEs (RLCKs) also associate with the complex, bifurcating the signal to key signaling hubs, such as MITOGEN-ACTIVATED PROTEIN KINASE (MAPK) cascades, to regulate diverse biological processes. Here, we discuss recent knowledge advances in understanding the roles of RLKs and RLPs in plant growth, development, and immunity, and their connection with co-regulatory receptors, leading to activation of diverse intracellular signaling pathways.
作为固着生物，植物会受到病原体入侵和环境波动的影响。为了克服周围环境的挑战，植物获得了感知内源性和外源性线索的潜力，从而具备了适应性。因此，植物进化出了大量的质膜驻留受体，包括受体样激酶（RLKs）和受体样蛋白（RLPs），以感知这些信号并调节植物的生长、发育和免疫。RLKs 和 RLPs 识别不同配体的能力依赖于进化出的多种细胞外结构域类别。通常需要共调节受体与 RLKs 和 RLPs 结合，以促进细胞信号转导。受体样细胞质激酶（RLCKs）也与该复合物结合，将信号分叉到关键信号枢纽，如丝裂原激活蛋白激酶（MAPK）级联，以调节多种生物学过程。在这里，我们讨论了最近在理解 RLKs 和 RLPs 在植物生长、发育和免疫中的作用方面的知识进展，以及它们与共调节受体的联系，导致多种细胞内信号通路的激活。
