Mutagenic action of phaseolinone, a mycotoxin isolated from Macrophomina phaseolina.
作者信息
Bhattacharya G, Dhar T K, Bhattacharyya F K, Siddiqui K A
机构信息
Indian Institute of Chemical Biology, Jadavpur, Calcutta.
出版信息
Aust J Biol Sci. 1987;40(4):349-53. doi: 10.1071/bi9870349.
PMID:3330928
Abstract
Phaseolinone was mutagenic to excision-repair-deficient strains of Escherichia coli WP2 and also to Salmonella typhimurium TA 100. The repair test was indicative of covalent binding of the toxin to DNA. The side-chain epoxide and the hydroxy groups of the molecule were found to be essential for mutagenic activity.
摘要
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