Department of Chemistry and Biochemistry, The University of Texas at Dallas, 800 West Campbell, BSB13, Richardson, Texas 75080-3021, USA.
Chem Soc Rev. 2021 Mar 1;50(4):2244-2259. doi: 10.1039/d0cs00589d.
The synthetic utility of aryl radicals has been established in the last century, however, their broad applications were hampered by ineffective generation methods. It was in the last decade, that a rapid development of various redox systems took place, thus triggering a renaissance of aryl radical chemistry. This tutorial review focuses on the start-of-the-art methods for generation of aryl radicals. Primarily, various light-induced systems, including photoredox catalysis, visible light transition metal catalysis, and chemistry of electron donor-acceptor complexes, are reviewed. The main current precursors of aryl radicals are evaluated together with the selected examples of their modern applications.
芳基自由基的合成实用性在上世纪已经确立，然而，其广泛的应用受到了低效生成方法的阻碍。直到过去十年，各种氧化还原体系才迅速发展起来，从而引发了芳基自由基化学的复兴。本专题评论集中于芳基自由基生成的最新方法。首先，综述了各种光诱导体系，包括光氧化还原催化、可见光过渡金属催化和电子给体-受体配合物化学。评估了芳基自由基的主要当前前体，并结合其现代应用的一些实例进行了选择。
