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2019 年 10 月至 12 月,希腊难民/移民接待中心出现耐多药志贺菌病例对公共卫生和临床的影响。

Public health and clinical implications of multidrug-resistant shigellosis cases in a reception centre for refugees/migrants, Greece, October-December 2019.

机构信息

Directorate of Epidemiological Surveillance and Intervention for Infectious Diseases, National Public Health Organization (NHPO), Athens, Greece.

Department of Public Health Policy, School of Public Health, National Reference Centre for Salmonella and Shigella, University of West Attica, West Attica, Greece.

出版信息

Eur J Public Health. 2021 Jul 13;31(3):588-590. doi: 10.1093/eurpub/ckaa220.

DOI:10.1093/eurpub/ckaa220
PMID:33313745
Abstract

From October to December 2019, 18 shigellosis cases (median age: 4.3 years, range: 0-21) were identified in the Reception Center for refugees/migrants on the Greek island of Samos. Fifteen cases (83.3%) were Afghani. Median time from arrival to symptoms onset was 53 days (40-101). Isolates from 14 cases, serotyped as Shigella flexneri 1b, and from three cases, serotyped as S. sonnei phase S (I), presented a multidrug-resistant phenotype. S. flexneri 1b isolates also produced extended-spectrum β-lactamases. Shigella flexneri 2a isolate from the remaining case was resistant to sulfomethoxazole, trimethoprim and pefloxacin. Improvement of hygiene and strengthening of laboratory investigation is needed.

摘要

2019 年 10 月至 12 月,在希腊萨摩斯岛的难民/移民接待中心发现了 18 例志贺氏菌病病例(中位年龄:4.3 岁,范围:0-21 岁)。15 例病例(83.3%)为阿富汗人。从抵达到出现症状的中位时间为 53 天(40-101 天)。从 14 例病例中分离出血清型为福氏志贺菌 1b 的菌株,从 3 例病例中分离出血清型为 S. sonnei 相 S(I)的菌株,呈现出多药耐药表型。福氏志贺菌 1b 分离株还产生了超广谱β-内酰胺酶。来自其余病例的福氏志贺菌 2a 分离株对磺胺甲恶唑、甲氧苄啶和培氟沙星耐药。需要改善卫生条件并加强实验室调查。

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