Department of Clinical and Translational Research, University of Rochester Medical Center, Rochester, NY.
Nicotine Tob Res. 2020 Dec 15;22(Suppl 1):S70-S75. doi: 10.1093/ntr/ntaa194.
The use of electronic cigarettes (vaping), especially with marijuana, has become increasingly popular among adults.
The Population Assessment of Tobacco and Health study Wave 4 data on 33 606 adult participants who indicated ever using electronic cigarettes were included in the study. By controlling for confounding variables (such as age and smoking history), multivariable weighted logistic regression models were used to examine the cross-sectional association between lifetime e-cigarette use with or without marijuana and self-reported past 12-month respiratory symptoms as well as lifetime respiratory diseases.
Compared to adults who never vaped, adults who had ever vaped with marijuana had a significantly higher association with self-reported past 12-month respiratory symptoms but not lifetime respiratory diseases. Compared to adults who had ever vaped without marijuana, adults who had ever vaped at least sometimes with marijuana had a significantly greater risk of having wheezing/whistling in the chest (adjusted odds ratio [aOR] = 1.21, 95% confidence interval [CI]: 1.01, 1.44), chest sounded wheezy during or after exercise (aOR = 1.59, 95% CI: 1.31, 1.93), and had a dry cough at night (aOR = 1.35, 95% CI: 1.16, 1.57), while adults who had ever vaped rarely with marijuana had a significantly greater risk of having wheezing/whistling in the chest (aOR = 1.31, 95% CI: 1.06, 1.61), chest sounded wheezy during or after exercise (aOR = 1.24, 95% CI: 1.01, 1.52), and had a dry cough at night (aOR = 1.24, 95% CI: 1.04, 1.47).
Lifetime e-cigarette use with marijuana is associated with self-reported past 12-month respiratory symptoms in adults.
The use of e-cigarettes with marijuana has become prevalent in recent years. Our cross-sectional study suggests that there may be respiratory health symptoms associated with ever vaping with marijuana that is independent of nicotine vaping, which should raise public awareness of potential health risks associated with the use of e-cigarettes with marijuana. Further longitudinal studies on the respiratory health effects of e-cigarette use with marijuana are warranted.
电子香烟（电子烟）的使用，尤其是与大麻一起使用，在成年人中变得越来越流行。
本研究纳入了 33606 名曾表示使用过电子烟的成年参与者的人口评估烟草和健康研究第四波数据。通过控制混杂变量（如年龄和吸烟史），使用多变量加权逻辑回归模型来检查终生电子烟使用（有或没有大麻）与自我报告的过去 12 个月呼吸道症状以及终生呼吸道疾病之间的横断面关联。
与从不吸电子烟的成年人相比，曾吸过电子烟（含大麻）的成年人与自我报告的过去 12 个月呼吸道症状显著相关，但与终生呼吸道疾病无关。与曾吸过不含大麻的电子烟的成年人相比，曾至少偶尔吸过含大麻的电子烟的成年人，胸部有哮鸣/哨音（调整后的优势比[aOR] = 1.21，95%置信区间[CI]：1.01，1.44）、运动时或运动后胸部有哮鸣音（aOR = 1.59，95% CI：1.31，1.93）和夜间干咳（aOR = 1.35，95% CI：1.16，1.57）的风险显著增加，而曾偶尔吸过含大麻的电子烟的成年人，胸部有哮鸣/哨音（aOR = 1.31，95% CI：1.06，1.61）、运动时或运动后胸部有哮鸣音（aOR = 1.24，95% CI：1.01，1.52）和夜间干咳（aOR = 1.24，95% CI：1.04，1.47）的风险显著增加。
终生电子烟使用（含大麻）与成年人自我报告的过去 12 个月呼吸道症状有关。
近年来，电子烟与大麻一起使用变得越来越流行。我们的横断面研究表明，与曾经使用含大麻的电子烟有关的可能存在呼吸道健康症状，这与尼古丁电子烟无关，这应该引起公众对与使用含大麻的电子烟相关的潜在健康风险的认识。需要进一步进行关于电子烟使用对大麻影响的纵向研究。
