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Isotretinoin in acne treatment during the coronavirus disease 2019 (COVID-19): A retrospective analysis of adherence to therapy and side effects.异维A酸在2019冠状病毒病（COVID-19）期间治疗痤疮的疗效：对治疗依从性和副作用的回顾性分析
Dermatol Ther. 2021 Jan;34(1):e14677. doi: 10.1111/dth.14677. Epub 2020 Dec 22.
2
Is systemic isotretinoin use a risk factor for coronavirus disease 2019 (COVID-19)?全身性使用异维甲酸是2019冠状病毒病（COVID-19）的一个风险因素吗？
J Cosmet Dermatol. 2021 Jun;20(6):1568-1570. doi: 10.1111/jocd.14044. Epub 2021 Mar 14.
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Oral isotretinoin treatment in patients with acne vulgaris during the COVID-19 pandemic: A retrospective cohort study in a tertiary care hospital.痤疮患者在 COVID-19 大流行期间口服异维 A 酸治疗：一家三级医院的回顾性队列研究。
J Cosmet Dermatol. 2021 Jul;20(7):1969-1974. doi: 10.1111/jocd.14168. Epub 2021 Apr 29.
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Isotretinoin Meets COVID-19: Revisiting a Fragmented Paradigm.异维A酸与新冠病毒：重新审视一个支离破碎的范例。
Cutis. 2021 Jul;108(1):8-12. doi: 10.12788/cutis.0299.
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Systemic isotretinoin therapy in the era of COVID-19.新冠疫情时代的系统性异维A酸疗法
Dermatol Ther. 2020 Jul;33(4):e13482. doi: 10.1111/dth.13482. Epub 2020 May 20.
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Analysis of clinical efficacy, side effects, and laboratory changes among patients with acne vulgaris receiving single versus twice daily dose of oral isotretinoin.寻常痤疮患者每日单次与每日两次口服异维甲酸的临床疗效、副作用及实验室检查变化分析。
Dermatol Ther. 2015 May-Jun;28(3):151-7. doi: 10.1111/dth.12213. Epub 2015 Mar 5.
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Could isotretinoin be a protective agent against COVID-19?: A dermatologist perspective.异维A酸能否成为对抗新型冠状病毒肺炎的保护剂？：皮肤科医生的观点。
J Cosmet Dermatol. 2021 Aug;20(8):2394-2395. doi: 10.1111/jocd.14239. Epub 2021 Jun 6.
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Effectiveness Of Oral Omega 3 In Reducing Mucocutaneous Side Effects Of Oral Isotretinoin In Patients With Acne Vulgaris.口服欧米伽 3 减少寻常痤疮患者口服异维 A 酸所致的黏膜炎和皮肤干燥等不良反应的疗效。
J Ayub Med Coll Abbottabad. 2021 Jan-Mar;33(1):60-63.
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Alopecia areata and isotretinoin; coincidence or causal relation.斑秃与异维A酸；巧合还是因果关系。
Dermatol Ther. 2020 May;33(3):e13280. doi: 10.1111/dth.13280. Epub 2020 Feb 28.
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A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.一种用于减轻痤疮患者口服异维A酸治疗副作用的膳食补充剂。
G Ital Dermatol Venereol. 2014 Aug;149(4):441-5.

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1
Prescribing and Dispensing of Oral Isotretinoin and Noncompliance with Recommendations in France before and during the COVID-19 Pandemic.法国在新冠疫情之前及期间口服异维A酸的处方与配药情况以及对相关建议的不依从性
Dermatol Ther (Heidelb). 2025 Jun;15(6):1533-1541. doi: 10.1007/s13555-025-01409-y. Epub 2025 Apr 18.
2
Association of Acne with Face Mask in Healthcare Workers Amidst the COVID-19 Outbreak in Karachi, Pakistan.巴基斯坦卡拉奇新冠疫情期间医护人员痤疮与口罩的关联
Clin Cosmet Investig Dermatol. 2021 Oct 7;14:1427-1433. doi: 10.2147/CCID.S333221. eCollection 2021.
3
Could isotretinoin be a protective agent against COVID-19?: A dermatologist perspective.异维A酸能否成为对抗新型冠状病毒肺炎的保护剂？：皮肤科医生的观点。
J Cosmet Dermatol. 2021 Aug;20(8):2394-2395. doi: 10.1111/jocd.14239. Epub 2021 Jun 6.
4
Oral isotretinoin treatment in patients with acne vulgaris during the COVID-19 pandemic: A retrospective cohort study in a tertiary care hospital.痤疮患者在 COVID-19 大流行期间口服异维 A 酸治疗：一家三级医院的回顾性队列研究。
J Cosmet Dermatol. 2021 Jul;20(7):1969-1974. doi: 10.1111/jocd.14168. Epub 2021 Apr 29.
5
Comment on "Androgens and women: COVID-19 outcomes in women with acne vulgaris, polycystic ovarian syndrome, and hirsutism".对《雄激素与女性：寻常痤疮、多囊卵巢综合征和多毛症女性的 COVID-19 结局》的评论
Int J Dermatol. 2021 Sep;60(9):e337-e338. doi: 10.1111/ijd.15617. Epub 2021 Apr 20.

本文引用的文献

1
Clinical symptoms of hyperandrogenic women diagnosed with COVID-19.被诊断患有新冠肺炎的高雄激素女性的临床症状。
J Eur Acad Dermatol Venereol. 2021 Feb;35(2):e101-e104. doi: 10.1111/jdv.17004. Epub 2020 Nov 8.
2
In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression.在体和体内鉴定能改变 ACE2 表达的临床批准药物。
Mol Syst Biol. 2020 Jul;16(7):e9628. doi: 10.15252/msb.20209628.
3
Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review.SARS-CoV-2 病毒的临床、分子和流行病学特征与 2019 年冠状病毒病（COVID-19）：全面文献复习。
Diagn Microbiol Infect Dis. 2020 Sep;98(1):115094. doi: 10.1016/j.diagmicrobio.2020.115094. Epub 2020 May 30.
4
Teledermatology for acne during COVID-19: high patients' satisfaction in spite of the emergency.新冠疫情期间痤疮的远程皮肤病学：尽管处于紧急状态，但患者满意度较高。
J Eur Acad Dermatol Venereol. 2020 Nov;34(11):e662-e663. doi: 10.1111/jdv.16746. Epub 2020 Jun 26.
5
Systemic isotretinoin therapy in the era of COVID-19.新冠疫情时代的系统性异维A酸疗法
Dermatol Ther. 2020 Jul;33(4):e13482. doi: 10.1111/dth.13482. Epub 2020 May 20.
6
Comparison of guidelines and consensus articles on the management of patients with acne with oral isotretinoin.关于口服异维A酸治疗痤疮患者管理的指南与共识文章的比较。
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):2229-2240. doi: 10.1111/jdv.16430. Epub 2020 May 14.
7
Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience.口服异维A酸治疗痤疮的挑战与解决方案：35年经验反思
Clin Cosmet Investig Dermatol. 2019 Dec 30;12:943-951. doi: 10.2147/CCID.S234231. eCollection 2019.
8
How to Increase Adherence and Compliance in Acne Treatment? A Combined Strategy of SMS and Visual Instruction Leaflet.如何提高痤疮治疗中的依从性和顺应性？SMS 和可视化指导手册相结合的策略。
Dermatology. 2019;235(6):463-470. doi: 10.1159/000502575. Epub 2019 Oct 4.
9
Effect of systemic isotretinoin therapy on mucociliary clearance and nasal surface mucosa in acne patients.系统性异维A酸治疗对痤疮患者黏液纤毛清除功能及鼻黏膜表面的影响。
J Drugs Dermatol. 2013 Aug;12(8):e124-8.

Isotretinoin in acne treatment during the coronavirus disease 2019 (COVID-19): A retrospective analysis of adherence to therapy and side effects.

作者信息

Donnarumma Marianna, Nocerino Mariateresa, Lauro Wanda, Annunziata Maria Carmela, Marasca Claudio, Fabbrocini Gabriella

机构信息

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

出版信息

Dermatol Ther. 2021 Jan;34(1):e14677. doi: 10.1111/dth.14677. Epub 2020 Dec 22.

DOI:10.1111/dth.14677
PMID:33320409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7883110/
Abstract
摘要