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噬菌体疗法患者中噬菌体穿透情况的研究。

Studies on bacteriophage penetration in patients subjected to phage therapy.

作者信息

Weber-Dabrowska B, Dabrowski M, Slopek S

机构信息

Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw.

出版信息

Arch Immunol Ther Exp (Warsz). 1987;35(5):563-8.

PMID:3332066
Abstract

Two healthy volunteers and 56 patients with suppurative bacterial infections were tested for penetration of oral administered bacteriophage to the blood circulation system and urinary tract. In the blood and urine samples collected from patients before phage therapy application, no presence of "wild phages" was confirmed. Examination performed on the 10th day of phage therapy revealed the presence of bacteriophages in 47 of 56 blood samples tested; positive result of examination was obtained in 9 cases of 26 urine samples.

摘要

对两名健康志愿者和56名化脓性细菌感染患者进行了测试,以检测口服噬菌体在血液循环系统和泌尿系统中的渗透情况。在噬菌体治疗应用前从患者采集的血液和尿液样本中,未确认存在“野生噬菌体”。在噬菌体治疗第10天进行的检查显示,在检测的56份血液样本中有47份存在噬菌体;在26份尿液样本中有9份检查结果呈阳性。

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