Thomas Xavier, Heiblig Maël
Department of Hematology, Lyon-Sud Hospital, Hospices Civils de Lyon, 69495 Pierre-Bénite, France.
Cancers (Basel). 2020 Dec 11;12(12):3718. doi: 10.3390/cancers12123718.
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML) cytogenetically characterized by a balanced reciprocal translocation between chromosomes 15 and 17, which results in the fusion between the promyelocytic leukemia () gene and retinoic acid receptor-α () [...].
急性早幼粒细胞白血病(APL)是急性髓系白血病(AML)的一种独特亚型,其细胞遗传学特征是15号和17号染色体之间发生平衡易位,导致早幼粒细胞白血病(PML)基因与维甲酸受体α(RAR-α)融合[...]。