Haugstvedt Aleksander Fjeld, Havsteen Inger Birgitte, Christensen Hanne
Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark.
Department of Radiology, Bispebjerg and Frederiksberg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark.
Neurol Res Pract. 2020 Oct 8;2:36. doi: 10.1186/s42466-020-00083-z. eCollection 2020.
Lumbar punctures are performed in different medical settings and are a key procedure in the diagnosis of several neurological conditions. Complications are rare and generally self-limiting. There are no reports of symptomatic accumulation of fluid in the epidural space after lumbar puncture in adults and there are no studies on long-term outcome after post dural puncture headache (PDPH).
A lumbar puncture was performed in a 29 y.o. slender woman with unspecific symptoms to rule out neuro-infection. Next day MRI showed substantial accumulation of CSF in the epidural space from C2 to the sacrum dislocating the spinal chord in the spinal canal. The condition was ameliorated by epidural blood-patching. At 5 months she was still impaired by severe orthostatic headache.
The only plausible explanation for the massive CSF leak was a dural tear occurring during multiple attempts of lumbar puncture. Anterior dislocation of the spinal chord due to CSF leak is not a recognised complication to lumbar puncture. This complication was followed by long-term disability in our case. The diagnosis can be made by MRI. A difficult procedure with several attempts and use of traumatic technique may increase risk of this complication.
腰椎穿刺在不同医疗环境中进行,是多种神经系统疾病诊断的关键操作。并发症罕见且通常为自限性。目前尚无成人腰椎穿刺后硬膜外间隙出现有症状性积液的报道,也没有关于腰穿后头痛(PDPH)长期预后的研究。
一名29岁身材苗条的女性因非特异性症状接受腰椎穿刺以排除神经感染。次日MRI显示从C2至骶部硬膜外间隙有大量脑脊液积聚,使椎管内脊髓移位。通过硬膜外血贴疗法病情得到改善。5个月时,她仍因严重的体位性头痛而受损。
大量脑脊液漏的唯一合理原因是多次腰椎穿刺尝试过程中发生的硬脑膜撕裂。脑脊液漏导致脊髓前脱位并非腰椎穿刺公认的并发症。在我们的病例中,这种并发症导致了长期残疾。可通过MRI做出诊断。操作困难且多次尝试以及使用创伤性技术可能会增加这种并发症的风险。