埃及开罗一家发热医院患者群体中非特异性发热和肌痛的虫媒病毒病因

Arboviral causes of non-specific fever and myalgia in a fever hospital patient population in Cairo, Egypt.

作者信息

Darwish M A, Feinsod F M, Scott R M, Ksiazek T G, Botros B A, Farrag I H, el Said S

机构信息

Ain Shams University Research and Training Center on Vectors of Diseases, Cairo, Egypt.

出版信息

Trans R Soc Trop Med Hyg. 1987;81(6):1001-3. doi: 10.1016/0035-9203(87)90378-6.

DOI:10.1016/0035-9203(87)90378-6

PMID:3332500

Abstract

Fever and myalgia are non-specific clinical manifestations of illness which commonly occur in patients with arboviral disease. In Egypt, such illness is often mis-diagnosed as "influenza". To determine arboviral aetiology in patients admitted with fever and myalgia, acute and convalescent sera samples were obtained from 55 patients admitted with these clinical manifestations to the Imbaba Fever Hospital, Giza, Egypt, during October and November 1984. Based on viral isolation, and a comparison of acute and convalescent sera, 4 patients (7%) had acute arboviral infections. Haemagglutination inhibition and indirect immunofluorescence tests showed that one had West Nile virus (WNV) infection, 2 had sandfly fever virus-Naples (SFN), and 1 had sandfly fever virus-Sicilian (SFS) infection. SFN was isolated from the acute serum sample of 1 of the 2 patients with SFN infection.

摘要

发热和肌痛是疾病的非特异性临床表现，常见于虫媒病毒病患者。在埃及，此类疾病常被误诊为“流感”。为确定发热和肌痛患者的虫媒病毒病因，于1984年10月和11月从埃及吉萨省因巴巴发热医院收治的55例有这些临床表现的患者中采集了急性期和恢复期血清样本。基于病毒分离以及急性期和恢复期血清的比较，4例患者（7%）发生了急性虫媒病毒感染。血凝抑制试验和间接免疫荧光试验显示，1例感染西尼罗河病毒（WNV），2例感染那不勒斯白蛉热病毒（SFN），1例感染西西里白蛉热病毒（SFS）。SFN从2例SFN感染患者中1例的急性期血清样本中分离出来。