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1 型糖尿病青少年情绪和焦虑障碍的患病率、病程以及症状严重程度的相关因素:来自糖尿病 LEAP 的结果。

Prevalence and course of mood and anxiety disorders, and correlates of symptom severity in adolescents with type 1 diabetes: Results from diabetes LEAP.

机构信息

Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands.

Department of Medical Psychology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

出版信息

Pediatr Diabetes. 2021 Jun;22(4):638-648. doi: 10.1111/pedi.13174. Epub 2021 Mar 16.

DOI:10.1111/pedi.13174
PMID:33331108
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8251968/
Abstract

OBJECTIVES

We aim to determine the prevalence and the course of anxiety and mood disorders in Dutch adolescents (12-18 years old) with type 1 diabetes, and to examine correlates of symptom severity, including parental emotional distress.

METHODS

Participants were 171 adolescents and 149 parents. The Diagnostic Interview Schedule for Children-IV was used to assess current, past year and lifetime anxiety and mood disorders in adolescents. Symptom severity and diabetes distress were measured with validated questionnaires. Correlates of these symptoms were examined using hierarchical regression analyses and included demographics (adolescent sex and age), clinical factors (diabetes duration, treatment modality, most recent glycated hemoglobin A ; all extracted from medical charts), adolescent diabetes distress, and parent emotional distress.

RESULTS

Twenty-four (14%) adolescents met the criteria for ≥1 disorder(s) in the previous 12 months. Anxiety disorders were more prevalent than mood disorders (13% vs. 4%). Lifetime prevalence of anxiety and mood disorders was 29% (n = 49). The presence of any of these disorders earlier in life (from 5 years old up to 12 months prior to assessment) was associated with disorders in the past 12 months (OR = 4.88, p = 0.001). Higher adolescent diabetes distress was related to higher symptoms of anxiety (b = 0.07, p = 0.001) and depression (b = 0.13, p = 0.001), while demographics, clinical characteristics, and parental emotional distress were not related.

CONCLUSIONS

Anxiety and mood disorders are common among adolescents and related to earlier disorders. Higher diabetes distress was related to higher symptom severity. Clinicians are advised to address past psychological problems and remain vigilant of these problems.

摘要

目的

我们旨在确定荷兰青少年(12-18 岁)1 型糖尿病患者焦虑和情绪障碍的患病率和病程,并研究症状严重程度的相关因素,包括父母的情绪困扰。

方法

研究对象为 171 名青少年和 149 名家长。使用儿童诊断访谈表第 IV 版评估青少年当前、过去一年和一生中的焦虑和情绪障碍。使用经过验证的问卷评估症状严重程度和糖尿病困扰。使用层次回归分析来研究这些症状的相关因素,包括人口统计学因素(青少年的性别和年龄)、临床因素(糖尿病持续时间、治疗方式、最近的糖化血红蛋白 A ;均从病历中提取)、青少年的糖尿病困扰和父母的情绪困扰。

结果

24 名(14%)青少年在过去 12 个月内符合≥1 种疾病的标准。焦虑症的患病率高于情绪障碍(13%对 4%)。焦虑和情绪障碍的终生患病率为 29%(n=49)。这些障碍在更早的生活中(从 5 岁到评估前 12 个月)的存在与过去 12 个月的障碍有关(OR=4.88,p=0.001)。较高的青少年糖尿病困扰与较高的焦虑症状(b=0.07,p=0.001)和抑郁症状(b=0.13,p=0.001)有关,而人口统计学、临床特征和父母的情绪困扰则无关。

结论

焦虑和情绪障碍在青少年中很常见,与早期障碍有关。较高的糖尿病困扰与较高的症状严重程度有关。临床医生应注意过去的心理问题,并对这些问题保持警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1c9/8251968/24be7f41256a/PEDI-22-638-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1c9/8251968/63a40026585b/PEDI-22-638-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1c9/8251968/24be7f41256a/PEDI-22-638-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1c9/8251968/63a40026585b/PEDI-22-638-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1c9/8251968/24be7f41256a/PEDI-22-638-g001.jpg

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