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一种新的白皮杉醇型倍半萜烯来自 Lindl.

A new picrotoxane-type sesquiterpene from Lindl.

机构信息

Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, PR China.

Nanjing Agricultural University, Nanjing, PR China.

出版信息

Nat Prod Res. 2022 Apr;36(8):2112-2117. doi: 10.1080/14786419.2020.1851224. Epub 2020 Dec 17.

DOI:10.1080/14786419.2020.1851224
PMID:33331167
Abstract

A picrotoxane-type sesquiterpene, dendroterpene E (), together with five benzene derivatives (), were isolated from the stems of Lindl. Their structures were elucidated by spectroscopic analysis and X-ray diffraction analysis. Compound was a new picrotoxane-type sesquiterpene with a C-9/C-1/O/C-11 oxetane ring, which was first encountered in this type of compounds. Compounds exhibited inhibitory activities against -glycosidase.

摘要

从细柄阿丁枫 Lindl. 的茎中分离得到一个吡咯烷酮型倍半萜()和五个苯衍生物()。通过光谱分析和 X 射线衍射分析确定了它们的结构。化合物是一个具有 C-9/C-1/O/C-11 氧杂环丁烷环的新型吡咯烷酮型倍半萜,在该类型化合物中首次发现。化合物对 -糖苷酶具有抑制活性。

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