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食物成瘾与烟草使用障碍:共同的发病机制和关联。

Food Addiction and Tobacco Use Disorder: Common Liability and Shared Mechanisms.

机构信息

Department of Pharmacology and Toxicology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

Centre for Addiction and Mental Health, 1025 Queen Street West, Toronto, ON M6J 1H4, Canada.

出版信息

Nutrients. 2020 Dec 15;12(12):3834. doi: 10.3390/nu12123834.

DOI:10.3390/nu12123834
PMID:33334010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7765398/
Abstract

As food addiction is being more commonly recognized within the scientific community, parallels can be drawn between it and other addictive substance use disorders, including tobacco use disorder. Given that both unhealthy diets and smoking are leading risk factors for disability and death, a greater understanding of how food addiction and tobacco use disorder overlap with one another is necessary. This narrative review aimed to highlight literature that investigated prevalence, biology, psychology, and treatment options of food addiction and tobacco use disorder. Published studies up to August 2020 and written in English were included. Using a biopsychosocial lens, each disorder was assessed together and separately, as there is emerging evidence that the two disorders can develop concurrently or sequentially within individuals. Commonalities include but are not limited to the dopaminergic neurocircuitry, gut microbiota, childhood adversity, and attachment insecurity. In addition, the authors conducted a feasibility study with the purpose of examining the association between food addiction symptoms and tobacco use disorder among individuals seeking tobacco use disorder treatment. To inform future treatment approaches, more research is necessary to identify and understand the overlap between the two disorders.

摘要

随着食物成瘾在科学界得到越来越多的认可,可以将其与其他成瘾物质使用障碍(包括烟草使用障碍)进行类比。鉴于不健康的饮食和吸烟都是导致残疾和死亡的主要风险因素,因此有必要更深入地了解食物成瘾和烟草使用障碍之间的相互关系。本综述旨在强调研究食物成瘾和烟草使用障碍的流行率、生物学、心理学和治疗选择的文献。纳入了截至 2020 年 8 月发表的、用英文撰写的研究。使用生物心理社会视角,综合评估了每种障碍,因为有新的证据表明这两种障碍可能在个体中同时或先后发生。共同点包括但不限于多巴胺能神经回路、肠道微生物群、儿童期逆境和依恋不安全感。此外,作者还进行了一项可行性研究,目的是检验寻求烟草使用障碍治疗的个体中食物成瘾症状与烟草使用障碍之间的关联。为了为未来的治疗方法提供信息,有必要进行更多的研究,以确定和理解这两种障碍之间的重叠。

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本文引用的文献

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Electronic cigarettes for smoking cessation.用于戒烟的电子烟。
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A Distinct Brain-Gut-Microbiome Profile Exists for Females with Obesity and Food Addiction.女性肥胖和食物成瘾存在独特的脑-肠-微生物组特征。
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Nutrients. 2020 Jun 26;12(6):1897. doi: 10.3390/nu12061897.
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Food cue reactivity in food addiction: A functional magnetic resonance imaging study.食物线索反应性与食物成瘾:一项功能磁共振成像研究。
Physiol Behav. 2019 Sep 1;208:112574. doi: 10.1016/j.physbeh.2019.112574. Epub 2019 Jun 7.
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Relationship between Food Dependence and Nicotine Dependence in Smokers: A Cross-Sectional Study of Staff and Students at Medical Colleges.吸烟者中食物依赖与尼古丁依赖的关系:对医科院校教职员工和学生的横断面研究。
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REPRINT OF: Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study.重印:童年期虐待及家庭功能障碍与成年人多种主要死因的关系:不良童年经历(ACE)研究
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