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埃塞俄比亚一家大型转诊医院糖尿病慢性并发症的患病率、模式及预测因素:一项前瞻性观察研究

Prevalence, Patterns and Predictors of Chronic Complications of Diabetes Mellitus at a Large Referral Hospital in Ethiopia: A Prospective Observational Study.

作者信息

Sheleme Tadesse, Mamo Girma, Melaku Tsegaye, Sahilu Tamiru

机构信息

Department of Pharmacy, College of Health Science, Mettu University, Mettu, Ethiopia.

School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.

出版信息

Diabetes Metab Syndr Obes. 2020 Dec 11;13:4909-4918. doi: 10.2147/DMSO.S281992. eCollection 2020.

Abstract

PURPOSE

Diabetes mellitus complications are responsible for increased disability, morbidity, and mortality. This study aimed to assess prevalence, patterns, and predictors of chronic complications of diabetes among people with diabetes.

PATIENTS AND METHODS

The study was conducted using a prospective observational study design which was done on people with diabetes attending the ambulatory clinic of Mettu Karl Referral Hospital. The data were collected using a consecutive type of sampling technique from April 15 to August 9, 2019. The data were entered into Epidata manager version 4.4.2. Logistic regression analysis was done to identify predictors of chronic complications of diabetes.

RESULTS

A total of 330 participants were included in this study. The mean age of participants was 49.9±14.2, and 156 (47.3%) were 41 to 60 years old. About 127 (38.5%) had one or more chronic complications. The predictors of chronic diabetes complications were resident in urban areas [AOR: 1.94; 95% CI: (1.17, 3.20); p = 0.010], duration of diabetes 10 years [AOR: 2.05, 95% CI: (1.21, 3.47); p = 0.007], hypertension [AOR: 4.19; 95% CI: (2.54, 6.91); p < 0.001] and poor glycemic control [AOR: 2.82; 95% CI: (1.53, 5.21); p = 0.001].

CONCLUSION

Almost two-fifth of the study participants had chronic complications of diabetes. Residents in urban areas, longer duration of diabetes, hypertension and poor glycemic control were predictors of chronic diabetes complications. It is important to achieve good glycemic control and manage comorbid diseases like hypertension to minimize the risk of chronic diabetes complications.

摘要

目的

糖尿病并发症会导致残疾、发病率和死亡率增加。本研究旨在评估糖尿病患者中慢性并发症的患病率、模式及预测因素。

患者与方法

本研究采用前瞻性观察性研究设计,对在梅图卡尔转诊医院门诊就诊的糖尿病患者进行研究。数据收集采用连续抽样技术,时间为2019年4月15日至8月9日。数据录入Epidata manager 4.4.2版本。进行逻辑回归分析以确定糖尿病慢性并发症的预测因素。

结果

本研究共纳入330名参与者。参与者的平均年龄为49.9±14.2岁,156名(47.3%)年龄在41至60岁之间。约127名(38.5%)有一项或多项慢性并发症。糖尿病慢性并发症的预测因素为居住在城市地区[AOR:1.94;95%CI:(1.17,3.20);p = 0.010]、糖尿病病程10年[AOR:2.05,95%CI:(1.21,3.47);p = 0.007]、高血压[AOR:4.19;95%CI:(2.54,6.91);p < 0.001]及血糖控制不佳[AOR:2.82;95%CI:(1.53,5.21);p = 0.001]。

结论

近五分之二的研究参与者患有糖尿病慢性并发症。城市居民、糖尿病病程较长、高血压及血糖控制不佳是糖尿病慢性并发症的预测因素。实现良好的血糖控制并管理高血压等合并症对于降低糖尿病慢性并发症风险很重要。

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