Amsalu Hailemariam, Hailu Molla, Asefa Adane, Ayenew Mengistu, Yosef Tewodros
School of Medicine, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Teferi, Ethiopia.
School of Public Health, College of Medicine and Health Sciences, Mizan-Tepi University, P.O.BOX: 260, Mizan-Teferi, Ethiopia.
Sci Rep. 2024 Aug 8;14(1):18428. doi: 10.1038/s41598-024-69527-9.
Ethiopia faces a significant challenge with increasing non-communicable diseases like diabetes, ranking among the top four in sub-Saharan Africa. However, there is a lack of research on how lifestyle affects chronic complications of diabetes in Ethiopia, highlighting the need for urgent exploration to develop better intervention strategies. This study aimed to evaluate the link between lifestyle factors and chronic complications of diabetes in public health hospitals in Southwest Ethiopia. A cross-sectional study involving 389 diabetes patients from Mizan-Tepi University Teaching Hospital (MTUTH) and Gebretsadik Shawo General Hospital (GSGH) in Southwest Ethiopia was conducted. Data collection methods included interviewer-administered questionnaires, patient medical record reviews, physical examination, and serum analysis. SPSS version 25 was used for data analysis, including descriptive statistics and bivariate and multivariate logistic regression analyses. Statistical significance was determined at a p-value < 0.05. The study revealed a 32.1% prevalence of chronic complications of diabetes, with 13.4% having chronic kidney disease, 8.0% experiencing visual disturbances, and 16.7% suffering from peripheral sensory pain. After adjusting for confounding variables, age (41-60 years [AOR = 1.77; 95% CI 1.01, 3.15] and > 60 years [AOR = 2.18; 95% CI 1.20, 4.33]), duration of diabetes mellitus (> 6 years [AOR = 2.90; 95% CI 1.74, 4.85]), alcohol consumption [AOR = 2.30; 95% CI 1.33, 3.98], physical inactivity [AOR = 2.43; 95% CI 1.38, 4.27], and body mass index (underweight [AOR = 7.66; 95% CI 1.68, 34.8] and obese [AOR = 3.53; 95% CI 1.84, 10.5]) were significantly associated with chronic complications of diabetes. Chronic complications of diabetes are a major problem in the study area. Lifestyle factors strongly influence chronic diabetes complications, highlighting the importance of preventive measures. Implementing health education and prevention programs focusing on modifiable lifestyle factors is crucial.
埃塞俄比亚在应对糖尿病等非传染性疾病不断增加方面面临重大挑战，在撒哈拉以南非洲排名前四。然而，在埃塞俄比亚，关于生活方式如何影响糖尿病慢性并发症的研究匮乏，这凸显了迫切需要进行探索以制定更好的干预策略。本研究旨在评估埃塞俄比亚西南部公共卫生医院中生活方式因素与糖尿病慢性并发症之间的联系。开展了一项横断面研究，涉及埃塞俄比亚西南部米赞-泰皮大学教学医院（MTUTH）和格布雷萨迪克·沙沃综合医院（GSGH）的389名糖尿病患者。数据收集方法包括访谈式问卷调查、患者病历审查、体格检查和血清分析。使用SPSS 25版进行数据分析，包括描述性统计以及双变量和多变量逻辑回归分析。当p值<0.05时确定具有统计学意义。该研究显示糖尿病慢性并发症的患病率为32.1%，其中13.4%患有慢性肾病，8.0%有视力障碍，16.7%患有周围感觉疼痛。在对混杂变量进行调整后，年龄（41 - 60岁[AOR = 1.77；95% CI 1.01，3.15]和>60岁[AOR = 2.18；95% CI 1.20，4.33]）、糖尿病病程（>6年[AOR = 2.90；95% CI 1.74，4.85]）、饮酒[AOR = 2.30；95% CI 1.33，3.98]、身体活动不足[AOR = 2.43；95% CI 1.38，4.27]以及体重指数（体重过轻[AOR = 7.66；95% CI 1.68，34.8]和肥胖[AOR = 3.53；95% CI 1.84，10.5]）与糖尿病慢性并发症显著相关。糖尿病慢性并发症是研究区域的一个主要问题。生活方式因素强烈影响糖尿病慢性并发症，凸显了预防措施的重要性。实施针对可改变生活方式因素的健康教育和预防项目至关重要。
