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尿石症:埃塞俄比亚一家三级护理医院的病例呈现与手术结果

Urolithiasis: Presentation and Surgical Outcome at a Tertiary Care Hospital in Ethiopia.

作者信息

Mohammed Seid, Yohannes Binyam, Tegegne Alemayehu, Abebe Kirubel

机构信息

Urology Unit, Department of Surgery, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Department of Surgery, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Res Rep Urol. 2020 Dec 8;12:623-631. doi: 10.2147/RRU.S284706. eCollection 2020.

Abstract

BACKGROUND

The prevalence of urolithiasis is on a rising trend in tropical and sub-Saharan African countries. The treatment options and data on the surgical outcome are limited in our country. This study was designed to assess the clinical presentation, surgical management and outcome of patients operated on for urolithiasis.

PATIENTS AND MATERIALS

A retrospective study of all patients admitted and operated for urolithiasis at St. Paul's hospital millennium medical college (SPHMMC) from July, 2016 to December, 2017 was conducted. Factors associated with surgical outcome were identified with binary logistic regression.

RESULTS

Urolithiasis constituted 247 (30.0%) of 824 urologic admissions. Of these, 202 (Male:Female = 2:1) patients were investigated. The mean age was 37.1 ± 14.4 years (range, 10-85 years). The mean duration of illness was 16.7 ± 18.7 months and the commonest presenting symptom was isolated flank pain (97, 48.0%). A majority of the patients (186, 92.1%) had upper tract stones of which 96 (51.6%) were renal stones. More than two-thirds (164, 81.2%) of the patients had complications at presentation, and hydronephrosis (148, 73.3%) was the major one. Half of the patients (104, 51.5%) were treated with endoscopic procedures, 88 (43.6%) with open stone surgery and in 10 (4.9%) patients both were performed. Nephrectomy was done to 15 (7.4%) patients. Intraoperative and postoperative complications were noted in 16 (7.9%) and 26 (12.9%) patients, respectively. These complications were higher in patients with comorbid illness (AOR = 2.44; 95% CI 1.12-5.31; p = 0.024). Complete stone clearance was achieved in more than half of the clients (114, 61.0%). Multiple stones (AOR = 8.33; 95% CI 2.53-27.43; p < 0.0001) and endoscopic procedures (AOR = 4.17; 95% CI 1.57-10.71; p = 0.003) had significant association with incomplete stone clearance.

CONCLUSION

Patients' presentation in this review was not different from studies elsewhere. Endoscopic procedures are emerging in our set up; however, it was significantly associated with incomplete stone clearance. Strategies to improve outcome (stone clearance) need to be implemented accordingly.

摘要

背景

在热带和撒哈拉以南非洲国家,尿石症的患病率呈上升趋势。我国尿石症的治疗选择及手术结果相关数据有限。本研究旨在评估接受尿石症手术患者的临床表现、手术治疗及结果。

患者与材料

对2016年7月至2017年12月在圣保罗医院千禧医学院(SPHMMC)收治并接受尿石症手术的所有患者进行回顾性研究。采用二元逻辑回归确定与手术结果相关的因素。

结果

尿石症占824例泌尿外科住院病例的247例(30.0%)。其中,对202例患者(男:女 = 2:1)进行了调查。平均年龄为37.1±14.4岁(范围10 - 85岁)。平均病程为16.7±18.7个月,最常见的症状是孤立性胁腹疼痛(97例,48.0%)。大多数患者(186例,92.1%)有上尿路结石,其中96例(51.6%)为肾结石。超过三分之二(164例,81.2%)的患者在就诊时出现并发症,肾盂积水(148例,73.3%)是主要并发症。一半的患者(104例,51.5%)接受了内镜手术治疗,88例(43.6%)接受了开放性结石手术,10例(4.9%)患者两种手术都做了。15例(7.4%)患者接受了肾切除术。术中及术后并发症分别在16例(7.9%)和26例(12.9%)患者中出现。合并症患者的这些并发症发生率更高(比值比 = 2.44;95%置信区间1.12 - 5.31;p = 0.024)。超过一半的患者(114例,61.0%)实现了结石完全清除。多发结石(比值比 = 8.33;95%置信区间2.53 - 27.43;p < 0.0001)和内镜手术(比值比 = 4.17;95%置信区间1.57 - 10.71;p = 0.003)与结石清除不完全显著相关。

结论

本综述中患者的表现与其他地方的研究无异。内镜手术在我们这里逐渐兴起;然而,它与结石清除不完全显著相关。需要相应地实施改善结果(结石清除)的策略。

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