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埃塞俄比亚补充维生素A与避免儿童死亡估计数:15年实践(2005 - 2019年)

Vitamin A supplementation and estimated number of averted child deaths in Ethiopia: 15 years in practice (2005-2019).

作者信息

Laillou Arnaud, Baye Kaleab, Zelalem Meseret, Chitekwe Stanley

机构信息

UNICEF Ethiopia, Addis Ababa, Ethiopia.

Center for Food Science and Nutrition, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Matern Child Nutr. 2021 Jul;17(3):e13132. doi: 10.1111/mcn.13132. Epub 2020 Dec 17.

Abstract

Vitamin A supplementation (VAS), started as a short-term strategy pending dietary improvements, has been implemented in Ethiopia for the last 15 years. We aimed to describe the trends in VAS coverage and estimated the associated reductions in child mortality. VAS coverage data obtained from the District Health Information System and the Demographic and Health Surveys were linked to child mortality data from the United Nations Interagency Group for Child Mortality Estimation (UN IGME). The number of child deaths averted was modelled assuming 12% and 24% reductions in all-cause mortality. From 2006 to 2011, VAS was delivered through campaigns, and coverage was above 85%. However, from 2011 onwards, VAS delivery was integrated to the routine health system, and the coverage declined to <60% with significant disparities by wealth quintile and rural-urban residence. VAS has saved between 167,563 to 376,030 child lives (2005-2019), but additional lives (>42,000) could have been saved with a universal coverage (95%). Inconsistent supply of vitamin A capsules, but more importantly, low access to health care, and the limited contact opportunities for children after 24 months may have contributed to the declining VAS coverage. Any changes in target or scale-up should thus consider these spatial and socioeconomic variations. Increasing the coverage of VAS and closing the equity gap in access to nutrition services is critical. However, with alternative programmes like vitamin A fortification being set-up, the benefits and safety of VAS need to be closely monitored, particularly in areas where there will be overlap.

摘要

作为在改善饮食之前的一项短期战略,维生素A补充计划(VAS)在埃塞俄比亚已实施了15年。我们旨在描述维生素A补充计划的覆盖趋势,并估计其对儿童死亡率的相关降低情况。从地区卫生信息系统和人口与健康调查中获取的维生素A补充计划覆盖数据,与联合国儿童死亡率估计机构间小组(UN IGME)的儿童死亡率数据相关联。假设全因死亡率降低12%和24%,对避免的儿童死亡人数进行了建模。2006年至2011年期间,通过运动开展维生素A补充计划,覆盖率超过85%。然而,从2011年起,维生素A补充计划的实施被纳入常规卫生系统,覆盖率降至60%以下,且在财富五分位数和城乡居住方面存在显著差异。维生素A补充计划在2005年至2019年期间挽救了167,563至376,030名儿童的生命,但如果实现普遍覆盖(95%),本可挽救更多生命(超过42,000名)。维生素A胶囊供应不稳定,但更重要的是,获得医疗保健的机会少,以及24个月后儿童的接触机会有限,可能导致了维生素A补充计划覆盖率的下降。因此,目标或扩大规模的任何变化都应考虑这些空间和社会经济差异。提高维生素A补充计划的覆盖率并缩小营养服务获取方面的公平差距至关重要。然而,随着维生素A强化等替代计划的设立,需要密切监测维生素A补充计划的益处和安全性,特别是在存在重叠的地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea1/8189216/5bd5c5836835/MCN-17-e13132-g002.jpg

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