Department of Food Science and Technology, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.
Department of Food Science, University of Guelph, Guelph, Ontario, Canada.
Compr Rev Food Sci Food Saf. 2020 Nov;19(6):2994-3030. doi: 10.1111/1541-4337.12614. Epub 2020 Aug 29.
The development of lipid-based delivery systems has attracted much attention over the last years and a wide variety of strategies and formulations are currently available to encapsulate, protect, and target delivery of bioactive and functional lipophilic constituents within the food and pharmaceutical industries. Waxes are crystalline lipid material, consisting of a complex mixture of long-chain fatty acids and fatty alcohols, hydrocarbons, aldehydes, and ketones and show great promises as constituents of carrier systems. Most of waxes are classified under food-grade category and show high availability at a low cost. This review article has provided a comprehensive summary of research on major carriers containing wax as one of the main constituents, including solid lipid nanoparticles, nanostructured lipid carriers, oleogels, and Pickering emulsions, with a focus on their food applications. The physical and chemical nature of natural waxes are described in the first while the second part deals with the structure, formulation, main methods of preparation, characterization, and finally utilization of each type of wax-based delivery system for specific food applications.
近年来,基于脂质的递药系统的发展引起了广泛关注,目前有多种策略和制剂可用于封装、保护和靶向生物活性和亲脂性成分在食品和制药行业中的递药。蜡是结晶性脂质材料,由长链脂肪酸和脂肪醇、烃类、醛类和酮类的复杂混合物组成,作为载体系统的组成部分具有很大的应用前景。大多数蜡都被归类为食品级,并以低成本大量供应。本文综述了以蜡为主要成分之一的主要载体的研究进展,包括固体脂质纳米粒、纳米结构脂质载体、油凝胶和 Pickering 乳液,重点介绍了它们在食品中的应用。第一部分描述了天然蜡的物理化学性质,第二部分则涉及每种蜡基递药系统的结构、配方、主要制备方法、特性以及最终在特定食品应用中的利用。