• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[不可逆性脑死亡的诊断:从移植管理人员角度看局限性及改进潜力]

[Diagnostics of irreversible brain death : Limitations and potential for improvement from the perspective of transplantation officials].

作者信息

Hoffmann Olaf Martin, Dinse Corinna, Masuhr Florian

机构信息

Klinik für Neurologie, Alexianer St. Josefs-Krankenhaus Potsdam, Allee nach Sanssouci 7, 14471, Potsdam, Deutschland.

Klinik für Neurologie, Bundeswehrkrankenhaus Berlin, Berlin, Deutschland.

出版信息

Anaesthesist. 2021 Jul;70(7):563-572. doi: 10.1007/s00101-020-00904-5. Epub 2020 Dec 18.

DOI:10.1007/s00101-020-00904-5
PMID:33337528
Abstract

BACKGROUND

In Germany, postmortem organ donation requires a diagnosis of irreversible brain death (BD) in strict compliance with the guidelines of the German Medical Association.

OBJECTIVE

Identification of factors that have a limiting effect on the initiation and execution of BD diagnostics. Identification of potential for improvement.

MATERIAL AND METHODS

Anonymous survey of transplantation officials in hospitals in Berlin, Brandenburg and Mecklenburg-Western Pomerania.

RESULTS

There is considerable heterogeneity with respect to the frequency of BD diagnostics and hospital-specific procedures, including the use of an existing consultation service. The local availability of qualified doctors and of suitable ancillary diagnostic tests has a structurally limiting effect. This is especially true for pediatric patients. Potential for improvement was seen in the identification of affected patients, the motivation of staff and the role of transplantation officials.

CONCLUSION

According to the recently amended German Transplantation Act, a centrally organized consultation service for BD diagnostics must be implemented as soon as 2021. Recommendations can be derived from the present survey and from the experience of the regionally established consultation service. In addition to neurological and neurosurgical expertise, qualified pediatricians and mobile ancillary instrumental diagnostics should also be provided. Expert advice from neurointensive care physicians should be available at an early stage in order to identify potentially affected patients. The highly variable participation of hospitals in organ donation, despite the availability of an expert diagnostic service free of charge, points to an important role of additional factors, some of which may be nonmedical in nature.

摘要

背景

在德国,尸检器官捐赠要求严格按照德国医学协会的指南诊断为不可逆脑死亡(BD)。

目的

确定对BD诊断的启动和实施具有限制作用的因素。确定改进潜力。

材料与方法

对柏林、勃兰登堡和梅克伦堡-前波美拉尼亚医院的移植官员进行匿名调查。

结果

在BD诊断频率和医院特定程序方面存在相当大的异质性,包括现有咨询服务的使用情况。合格医生和合适辅助诊断测试的本地可用性具有结构性限制作用。儿科患者尤其如此。在受影响患者的识别、工作人员的积极性和移植官员的作用方面存在改进潜力。

结论

根据最近修订的德国《移植法》,最迟在2021年必须实施一项针对BD诊断的中央组织咨询服务。可以从本次调查以及地区性咨询服务的经验中得出建议。除了神经科和神经外科专业知识外,还应提供合格的儿科医生和移动辅助仪器诊断。神经重症监护医生的专家建议应尽早提供,以便识别可能受影响的患者。尽管有免费的专家诊断服务,但医院在器官捐赠方面的参与程度差异很大,这表明其他因素起着重要作用,其中一些因素可能是非医学性质的。

相似文献

1
[Diagnostics of irreversible brain death : Limitations and potential for improvement from the perspective of transplantation officials].[不可逆性脑死亡的诊断:从移植管理人员角度看局限性及改进潜力]
Anaesthesist. 2021 Jul;70(7):563-572. doi: 10.1007/s00101-020-00904-5. Epub 2020 Dec 18.
2
[Ancillary procedures in the diagnostics of brain death. Utilization, results and consequences in northeastern Germany].[脑死亡诊断中的辅助程序。德国东北部的应用、结果及影响]
Nervenarzt. 2016 Feb;87(2):169-77. doi: 10.1007/s00115-015-0044-2.
3
[Diagnosis of brain death in Germany-Implementation of the guidelines of the German Medical Association].[德国脑死亡的诊断——德国医学协会指南的实施]
Nervenarzt. 2023 Dec;94(12):1129-1138. doi: 10.1007/s00115-023-01520-5. Epub 2023 Jul 18.
4
[Access to brain death diagnostics].[脑死亡诊断方法]
Nervenarzt. 2014 Dec;85(12):1573-81. doi: 10.1007/s00115-014-4171-y.
5
[Brain Death and Treatment of (Potential) Organ Donors and Interactions with their Relatives].[脑死亡与(潜在)器官捐献者的治疗及其与亲属的互动]
Anasthesiol Intensivmed Notfallmed Schmerzther. 2020 Jul;55(7-08):453-466. doi: 10.1055/a-1167-1420. Epub 2020 Jul 31.
6
[How many potential organ donors are there really? : Retrospective analysis of why determination of irreversible loss of brain function was not performed in deceased patients with relevant brain damage].究竟有多少潜在器官捐献者?:对相关脑损伤死亡患者未进行脑功能不可逆丧失判定原因的回顾性分析
Anaesthesist. 2019 Jan;68(1):22-29. doi: 10.1007/s00101-018-0510-x. Epub 2018 Nov 16.
7
[Post-mortem organ donation].[尸体器官捐赠]
Anaesthesist. 2015 Jul;64(7):543-56; quiz 557-8. doi: 10.1007/s00101-015-0054-2.
8
[Acceptance of post-mortem organ donation in Germany : Representative cross-sectional study].[德国对死后器官捐赠的接受情况:代表性横断面研究]
Anaesthesist. 2018 Feb;67(2):118-125. doi: 10.1007/s00101-017-0391-4. Epub 2017 Dec 11.
9
[Diagnosis of irreversible loss of brain function ("brain death")-what is new?].[不可逆性脑功能丧失(“脑死亡”)的诊断——有哪些新进展?]
Nervenarzt. 2019 Oct;90(10):1021-1030. doi: 10.1007/s00115-019-0765-8.
10
[Revised organ transplantation act in Japan from the view of emergency doctors].[从急诊医生角度看日本修订后的器官移植法]
Brain Nerve. 2010 Jun;62(6):565-73.

引用本文的文献

1
[Diagnosis of brain death in Germany-Implementation of the guidelines of the German Medical Association].[德国脑死亡的诊断——德国医学协会指南的实施]
Nervenarzt. 2023 Dec;94(12):1129-1138. doi: 10.1007/s00115-023-01520-5. Epub 2023 Jul 18.

本文引用的文献

1
[Amendments to the Transplantation Act and impact on the donor situation in Germany].[《移植法》修正案及其对德国供体情况的影响]
Chirurg. 2020 Nov;91(11):905-912. doi: 10.1007/s00104-020-01242-3.
2
[Diagnosis of irreversible loss of brain function ("brain death")-what is new?].[不可逆性脑功能丧失(“脑死亡”)的诊断——有哪些新进展?]
Nervenarzt. 2019 Oct;90(10):1021-1030. doi: 10.1007/s00115-019-0765-8.
3
[Decision-making support in Intensive Care to facilitate organ donation : Position paper of the Ethics Section and the Organ Donation and Transplantation Section of the German Interdisciplinary Association of Critical Care and Emergency Medicine (DIVI) in collaboration with the Ethics Section of the German Society of Medical Intensive Care Medicine and Emergency Medicine (DGIIN)].
重症监护中促进器官捐献的决策支持:德国重症监护与急诊医学跨学科协会(DIVI)伦理委员会及器官捐献与移植委员会与德国医学重症监护与急诊医学学会(DGIIN)伦理委员会合作发布的立场文件
Med Klin Intensivmed Notfmed. 2019 May;114(4):319-326. doi: 10.1007/s00063-019-0578-3.
4
[How many potential organ donors are there really? : Retrospective analysis of why determination of irreversible loss of brain function was not performed in deceased patients with relevant brain damage].究竟有多少潜在器官捐献者?:对相关脑损伤死亡患者未进行脑功能不可逆丧失判定原因的回顾性分析
Anaesthesist. 2019 Jan;68(1):22-29. doi: 10.1007/s00101-018-0510-x. Epub 2018 Nov 16.
5
[Amendment to the documentation of decisions to withhold or withdraw life-sustaining therapies in consideration of wish to donate organs : Recommendation of the Ethics Section and the Organ Donation and Transplantation Section of the German Interdisciplinary Association of Critical Care and Emergency Medicine (DIVI) in collaboration with the Ethics Section of the German Society of Medical Intensive Care Medicine and Emergency Medicine (DGIIN)].[考虑器官捐赠意愿时关于停止或撤销维持生命治疗决策的文件修订:德国重症与急诊医学跨学科协会(DIVI)伦理委员会及器官捐赠与移植委员会与德国重症医学与急诊医学学会(DGIIN)伦理委员会联合发布的建议]
Med Klin Intensivmed Notfmed. 2019 Feb;114(1):53-55. doi: 10.1007/s00063-018-0509-8.
6
[New Challenges: Diagnosis of Brain Death in Newborn, Children and Adolescents].[新挑战:新生儿、儿童及青少年脑死亡的诊断]
Klin Padiatr. 2018 Mar;230(2):88-96. doi: 10.1055/s-0043-124677. Epub 2018 Jan 17.
7
Use of Observational Periods or Ancillary Tests in the Determination of Brain Death in Germany.德国在脑死亡判定中观察期或辅助检查的应用
Eur Neurol. 2015;74(1-2):11-7. doi: 10.1159/000431089. Epub 2015 Jun 13.
8
[Access to brain death diagnostics].[脑死亡诊断方法]
Nervenarzt. 2014 Dec;85(12):1573-81. doi: 10.1007/s00115-014-4171-y.
9
[Change in therapy target and therapy limitations in intensive care medicine. Position paper of the Ethics Section of the German Interdisciplinary Association for Intensive Care and Emergency Medicine].[重症医学中治疗目标的变化与治疗局限性。德国重症与急诊医学跨学科协会伦理委员会立场文件]
Anaesthesist. 2013 Jan;62(1):47-52. doi: 10.1007/s00101-012-2126-x.
10
Second brain death examination may negatively affect organ donation.再次进行脑死亡判定可能会对器官捐献产生负面影响。
Neurology. 2011 Jan 11;76(2):119-24. doi: 10.1212/WNL.0b013e3182061b0c. Epub 2010 Dec 15.