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加纳 5 岁以下儿童贫血与腹泻的合并模式:多变量复杂抽样逻辑回归分析和空间映射可视化。

Comorbid patterns of anaemia and diarrhoea among children aged under 5 years in Ghana: a multivariate complex sample logistic regression analysis and spatial mapping visualisation.

机构信息

Research Department, FOCOS Orthopaedic Hospital, Accra, Ghana.

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, TX, USA.

出版信息

Int Health. 2021 Dec 1;13(6):562-572. doi: 10.1093/inthealth/ihaa099.

Abstract

BACKGROUND

Anaemia and diarrhoea are known independent causes of under-five morbidity and mortality. This study sought to investigate predictors of comorbid patterns of anaemia and diarrhoea using the 2014 Ghana Demographic and Health Survey (GDHS).

METHODS

The study employed analysis of secondary data from the 2014 GDHS. We performed a multivariate complex sample logistic regression and spatial analysis.

RESULTS

The weighted prevalence of comorbid anaemia and diarrhoea was 9.28% with the highest burden (16.45%) found in the Upper West region. Independent predictors (risk factors) of comorbid patterns of anaemia and diarrhoea were children aged 6-23 mo (OR=2.17, 95% CI 1.42 to 3.33), male gender (OR=1.50, 95% C1 1.04 to 2.16), history of fever (OR=4.37, 95% CI 2.94 to 6.50) and living in a household with two children aged <5 y (OR=1.80, 95% CI 1.14 to 2.84). Protective factors were having a father with secondary or higher education (OR=0.57, 95% CI 0.33 to 0.97), living in a household with ≥6 members (OR=0.46, 95% CI 0.28 to 0.75) and living in a richer household (OR=0.38, 95% CI 0.16 to 0.89). Surface maps revealed inter-regional and subregional variations.

CONCLUSION

The study shows that the independent predictors of comorbid patterns of anaemia and diarrhoea among children aged <5 y in Ghana are age, gender, history of fever, the number of children aged <5 y in the household, parental education, household size and household wealth. The study identified zones to be targeted for cost-effective policy interventions.

摘要

背景

贫血和腹泻是导致五岁以下儿童发病和死亡的已知独立原因。本研究旨在利用 2014 年加纳人口与健康调查(GDHS)调查贫血和腹泻合并模式的预测因素。

方法

本研究采用 2014 年 GDHS 的二次数据分析。我们进行了多变量复杂样本逻辑回归和空间分析。

结果

合并贫血和腹泻的加权患病率为 9.28%,其中上西部地区的负担最重(16.45%)。贫血和腹泻合并模式的独立预测因素(危险因素)为 6-23 月龄儿童(OR=2.17,95%CI 1.42-3.33)、男性(OR=1.50,95%CI 1.04-2.16)、发热史(OR=4.37,95%CI 2.94-6.50)和家中有 2 名 5 岁以下儿童(OR=1.80,95%CI 1.14-2.84)。保护因素包括父亲接受过中等或高等教育(OR=0.57,95%CI 0.33-0.97)、家中有 6 名或更多成员(OR=0.46,95%CI 0.28-0.75)和家庭较富裕(OR=0.38,95%CI 0.16-0.89)。表面地图显示了区域间和次区域间的差异。

结论

本研究表明,加纳 5 岁以下儿童合并贫血和腹泻的独立预测因素为年龄、性别、发热史、家中 5 岁以下儿童人数、父母教育程度、家庭规模和家庭财富。该研究确定了需要针对这些因素进行具有成本效益的政策干预的区域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5b1/8643461/a1f54f92ccd8/ihaa099fig1.jpg

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