Department of Abdominal, Tumor, Transplant and Vascular Surgery, Cologne-Merheim Medical Center, Witten/Herdecke University, Ostmerheimer Strasse 200, 51109, Cologne, Germany.
Sci Rep. 2020 Dec 18;10(1):22321. doi: 10.1038/s41598-020-79461-1.
The aim was to compare short-term results of transvaginal hybrid-NOTES (NSR) with traditional laparoscopic technique in sigmoid resection (LSR) in cases of diverticulitis. Natural Orifice Transluminal Endoscopic Surgery has been evolved as a minimally invasive procedure to reduce the operative trauma due to the absence of specimen extraction through the abdominal wall causing less postoperative pain, and shorter hospital stay. Despite the increasing use and published case series of NSR for diverticulitis as a laparoscopic procedure with transvaginal stapling and specimen extraction, there are no studies comparing this procedure with LSR. Twenty NSR patients operated at the Cologne-Merheim Medical Center have been documented and compared with 20 female LSR patients matched for body mass index, American Society of Anesthesiologists-classification (ASA), Hansen/Stock classification, and age. To ensure comparability regarding peri- and postoperative care, only procedures performed by the same surgeon were included. Procedural time, intra- and postoperative complications, conversion rate, postoperative pain, the duration of an epidural catheter, analgesic consumption, and postoperative length of hospital stay were analyzed. There were no significant differences in the sum of pain levels (p = 0.930), length of procedure (p = 0.079), intra- and postoperative complications, as well as duration of an epidural catheter. On the contrary, there were significant positive effects for NSR on morphine requirement at day seven and eight (p = 0.019 and p = 0.035 respectively) as well as the postoperative length of hospital stay (p = 0.031). This retrospective study reveals significant positive effects for NSR compared to LSR regarding length of hospital stay as well as morphine consumption after removal of the epidural catheter, whereas there were no significant differences in complication rate and procedural time. In summary, NSR is an adequate alternative to traditional laparoscopic sigmoid resection considering the surgeons experience and the patient's personal preferences.
目的是比较经阴道混合NOTES(NSR)与传统腹腔镜技术在憩室炎患者乙状结肠切除术中的短期结果。由于不需要通过腹壁提取标本,因此经自然腔道内镜外科手术已演变为一种微创程序,可减少因手术引起的创伤,术后疼痛减轻,住院时间缩短。尽管 NSR 作为一种经阴道吻合和标本提取的腹腔镜手术,在憩室炎中的应用越来越多,并发表了一系列病例系列,但尚无将该手术与 LSR 进行比较的研究。科隆-梅尔海姆医疗中心记录了 20 例 NSR 患者,并与 20 例女性 LSR 患者进行了匹配,这些患者的体重指数、美国麻醉医师协会分类(ASA)、Hansen/Stock 分类和年龄相匹配。为了确保围手术期护理的可比性,仅纳入由同一位外科医生进行的手术。分析了手术时间、围手术期和术后并发症、转化率、术后疼痛、硬膜外导管使用时间、镇痛消耗和术后住院时间。两组患者的疼痛评分总和(p=0.930)、手术时间(p=0.079)、围手术期并发症以及硬膜外导管使用时间均无显著差异。相反,NSR 在第 7 天和第 8 天吗啡需求方面具有显著的积极影响(p=0.019 和 p=0.035)以及术后住院时间(p=0.031)。这项回顾性研究表明,与 LSR 相比,NSR 在住院时间和硬膜外导管拔除后的吗啡消耗方面具有显著的积极影响,而并发症发生率和手术时间无显著差异。总之,考虑到外科医生的经验和患者的个人喜好,NSR 是传统腹腔镜乙状结肠切除术的一种合适替代方法。