Department of Radiology, MINAR Cancer Hospital, Multan, Pakistan.
Department of Surgery, Children Complex, Multan, Pakistan.
J Pak Med Assoc. 2020 Nov;70(11):2051-2053. doi: 10.5455/JPMA.48120.
Primary Breast cancer is the most common malignancy in females but secondary involvement of breast is very rare. The Most common sites of primaries for breast metastasis are breast carcinoma of contra lateral side, Lymphoma and leukaemia. Medullary Thyroid Carcinoma (MTC) itself is rare and commonly metastasises to liver, lung and bones. Secondary breast involvement by MTC is very rare with only few case reports in literature. Clinically and radiographically breast secondaries mimic benign lesions and may cause diagnostic challenges. To avoid unnecessary surgery and for appropriate treatment decision,accurate diagnosis is important. We present here our experience of a similar case of secondary breast carcinoma from MTC seen at MINAR cancer hospital Multan. The patient presented clinically and radiologically with benign breast lumps. Fine needle aspiration (FNAC) showed atypical cells and Ultra sound guided Trucut biopsy confirmed it to be a secondary from MTC. Patient is under treatment of an oncologist, has been treated with chemotherapy and is on follow up till date.
原发性乳腺癌是女性最常见的恶性肿瘤，但乳房的继发性受累非常罕见。乳房转移的最常见原发性肿瘤部位是对侧乳房癌、淋巴瘤和白血病。甲状腺髓样癌（MTC）本身很少见，通常转移到肝脏、肺和骨骼。MTC 引起的继发性乳腺癌非常罕见，文献中仅有少数病例报告。临床上和影像学上，乳腺继发性肿瘤类似于良性病变，可能导致诊断挑战。为了避免不必要的手术和进行适当的治疗决策，准确的诊断很重要。我们在此介绍在 Multan 的 MINAR 癌症医院看到的一例来自 MTC 的继发性乳腺癌的类似病例。该患者临床表现和影像学上均表现为良性乳腺肿块。细针抽吸（FNAC）显示非典型细胞，超声引导 Trucut 活检证实为 MTC 的继发性肿瘤。患者正在接受肿瘤学家的治疗，已接受化疗，并在随访中。
